This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang +16 more
wiley +1 more source
Conserving Large Old Trees in Guangxi, South China: Diversity, Distribution, and Preservation Strategies. [PDF]
Yan J +6 more
europepmc +1 more source
The Effective Provision of Pre-School Education (EPPE) Project: Measuring the Impact of Pre-School on Children's Social/Behavioural Development over the Pre-School Period [PDF]
Elliot, Karen +5 more
core +1 more source
Global Nitrogen Deposition Promotes Carbon Sink Formation in Terrestrial Ecosystems
Nitrogen deposition alleviates ecosystem N limitation and enhances carbon sinks. Using 829 observations, we show 36% of deposited N is retained globally (39.15 Tg N yr−1), with distinct NHx and NOy contributions. This retention drives a terrestrial C sink of 0.88 Pg C yr−1 (25.48%), highlighting the importance of pool‐specific C:N stoichiometry ...
Lei Li +6 more
wiley +1 more source
LED lighting and exogenous cytokinin enhance budbreak and winter growth of 'Washington' navel orange in the nursery. [PDF]
de Carvalho DU +3 more
europepmc +1 more source
Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang +4 more
wiley +1 more source
Host-Adaptive Divergence Shapes the Genetic Architecture of <i>Magnaporthe oryzae</i> in Southern China's Rice Agroecosystems. [PDF]
Liu X +15 more
europepmc +1 more source
Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma +11 more
wiley +1 more source

