Results 121 to 130 of about 8,546,097 (246)

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen   +7 more
wiley   +1 more source

OKULÖNCESİDÖNEMDEKİÇOCUKLARIN DUYGUSAL YÜZ İFADELERİNİTANIMA BECERİLERİNİN ÇEŞİTLİ DEĞİŞKENLER AÇISINDAN İNCELENMESİ

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2004
Bu araştırmada, anasınıfına devam eden çocukların duygusal yüz ifadelerini tanıma becerilerini etkileyen bazıdeğişkenler incelenmiştir. Araştırmanın bağımlıdeğişkeni duygusal yüz ifadelerini tanıma becerileridir.
Ramazan Arı, Zarife Şahin Seçer
doaj  

Psychological distress and associated factors among Japanese nursery school and kindergarten teachers: a cross-sectional study. [PDF]

open access: yesInd Health, 2020
Yaginuma-Sakurai K   +6 more
europepmc   +1 more source

Graphene‐Engineered Rear Interfaces Enable Efficient Flexible CZTSSe Solar Cells on Metal Foils

open access: yesAdvanced Science, EarlyView.
An atomically thin graphene interlayer stabilizes the rear interface of flexible CZTSSe solar cells by regulating interfacial stress, suppressing detrimental interfacial reactions, and reducing the back‐contact barrier. This strategy simultaneously improves photovoltaic performance and mechanical durability.
Yixiong Ji   +18 more
wiley   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

open access: yesAdvanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan   +5 more
wiley   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang   +12 more
wiley   +1 more source

Development of Children's Creative Activity in Preschool

open access: yesMultidisciplinary Journal of School Education, 2019
An essential element of the teaching system, which is of vital importance, is the set of educational methods. A prominent place amongst these is occupied by those methods that develop creative activity; this is because the main element that results in ...
Anna Klim-Klimaszewska
doaj  

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen   +10 more
wiley   +1 more source

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