Results 121 to 130 of about 2,699,017 (390)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Outcomes of Simulation-Based Education on Prelicensure Nursing Students’ Preparedness in Identifying a Victim of Human Trafficking

Social Sciences
Background: Individuals who are victimized and exploited by the heinous crimes of human trafficking (HT) access healthcare during their exploitation, yet gaps in education on HT content exist in prelicensure nursing programs.
Debra McWilliams, Geraldine Cornell, Francine Bono-Neri   +2 more
doaj   +1 more source

Helplessness or self care? : a study of nursing practice with depressed patients in an in-care setting : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Nursing Studies at Massey University [PDF]

, 1982
This study was conducted to investigate the practice of nurses when working with depressed patients in an in care setting. A survey of the literature shows that the role commonly prescribed for nurses who work in psychiatric settings is one that ...
Butterfield, Shona
core  

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Barriers to end-of-life discussion with advanced cancer patient as perceived by oncologists, certified/specialized nurses in cancer nursing and medical social workers [PDF]

, 2020
Yasutaka Kimura, Miki Hosoya, Kyoko Toju, Chikako Shimizu, Tatsuya Morita   +4 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Response to “An overview of health workforce education and accreditation in Africa: implications for scaling-up capacity and quality”

Human Resources for Health, 2023
Alex Berland, Helen Ewing, Kathleen Capone, Erica Frank, Miriam Chickering   +4 more
doaj   +1 more source

The skills and brain drain what nurses say [PDF]

, 2013
Aims and objectives. To explore sub-Saharan African nurses' reasons for moving to the UK, their views on the skills and brain drain, and what can be done to stem the situation. Background.
Likupe, Gloria
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Nurses\u27 Alumnae Association Bulletin - Volume 6 Number 9 [PDF]

, 1948
Remember the Relief Fund Welcome! Miss Childs Financial Report Calendar of Coming Events Lest You Forget! Attention Review of the Alumnae Association Meetings Institutional Staff Nurses\u27 Section Report of Staff Activities - 1947-1948 Private Duty ...
Allbritton, Frank F, Bauer, Mrs. Edward L, Beatty, Dorothy M, Bonenberger, Mary, Carey, Margaret A, Childs, Katherine, Dute, Evelyn, Erf, Lowell, Flack, Henrietta L, Montgomery, Thaddeus L, Piersol, Betty, Price, Allison, Ranck, Dorothy, Shoemaker, Nora E, Spruance, Henrietta F, Walker, Martha, Walters, Elsie M   +16 more
core   +1 more source