Results 31 to 40 of about 886,923 (294)

Occupational Stress, Psychological Distress, Physical Symptoms, and their Interrelationships among Frontline Nurses Treating Patients with COVID-19 [PDF]

, 2021
Tomoe Nishihara, Kazufumi Yoshihara, Ayako Ohashi, Mika Kuroiwa, Nobuyuki Sudo   +4 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Öğrenci ve Öğretmenlerin Kariyer Algılarının İncelenmesi

Sakarya Üniversitesi Eğitim Fakültesi Dergisi, 2017
1970’li yıllarda ele alınmaya başlanan kariyer kavramıson zamanlarda iş literatüründe sıkça kullanılan bir sözcük haline gelmiştir.Kariyer, bir insanın çalışabileceği yıllar boyunca herhangi bir iş alanındaadım adım ve sürekli olarak ilerlemesi, deneyim ...
Fuat Tanhan, Doğan Nurses
doaj  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The quality and applicability of clinical practice guidelines for falls prevention, assessment and management across the lifespan: A systematic review

International Journal of Nursing Studies Advances
Background: The burden of falls across the lifespan is substantial. Given the variety of clinical practice guidelines available for falls management, it is useful to understand the quality and clinical applicability of guidelines and their ...
Amber Harnett, Lyndsay Howitt, Vithusa Kumarasamy, Christine Buchanan, Amy Burt, Nafsin Nizum, Shanoja Naik   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The effect of social media use on nursing students’ general fatigue: The mediating roles of academic engagement and academic procrastination

International Journal of Africa Nursing Sciences
Background: Social media addiction is increasingly prevalent among students and has been linked to negative academic and psychological outcomes. Understanding the mechanisms through which SMA impacts student well-being, particularly fatigue, remains ...
Rashidatu Monne, Mudasir Mohammed Ibrahim, Abubakari Wuni, Barratu Issah, Flavia A. Atirekpere, Munira Abdul-Razak, Abdul Latif Abdul Rahaman, Iddrisu Mohammed Sisala   +7 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

“We Are Our Own Worst Enemies”: Workplace Bullying Among Nurses and Its Implications on Healthcare Workers and Job Performance: A Multi‐Facility Study in the Tamale Metropolis

Nursing Open
Background Workplace bullying is an important issue confronting the nursing profession, with victims described as being part of an oppressed group. The number of attacks and acts of violence that staff direct at each other in the workplace is alarmingly ...
Abubakari Wuni, Ajara Musah, Iddrisu Mohammed Sisala, Abdul Malik Abdulai, Letitia Chanayireh, Brenda Abena Nyarko, Hannah Buasilenu, Mudasir Mohammed Ibrahim, Sulemana Musah, Dorothy Azure, Nafisah Abdulai   +10 more
doaj   +1 more source

RNAO’s Artificial Intelligence Innovations: A Novel Strategy to Advance Evidence-Based Nursing Practice

MedUNAB
Introduction. Artificial intelligence and machine learning methodologies, such as prediction, pattern recognition, or general inference based on the data used in clinical aspects, must fit within the intended purposes of developing it.
Naik, Shanoja, Grinspun, Doris
doaj   +1 more source