Results 241 to 250 of about 932,092 (324)

The potential role of environmentally associated DNA methylation in childhood acute lymphoblastic leukaemia subtypes

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The rarity of acute lymphoblastic leukaemia and lack of available environmental data have made the role of environmental factors in genetic subtypes challenging to investigate. Here, the authors performed a CpG‐level analysis to investigate DNA methylation as an intermediate mechanism between environmental risk exposures and acute ...
Jessica R. Saville   +5 more
wiley   +1 more source

Workforce outcomes among substance use peer supports: a scoping review of individual and organizational influences. [PDF]

open access: yesFront Public Health
Bell JS   +7 more
europepmc   +1 more source

Understanding delays in breast cancer diagnosis in Africa: Key insights and contributing factors

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Despite lower incidence rates, Africa has the highest age‐standardized breast cancer mortality rates globally. Using Bronfenbrenner's ecological model to classify multilevel influences on the individual, this scoping review shows that a lack of knowledge about breast cancer is the primary factor contributing to breast cancer diagnostic ...
Liza A. Hoveling   +6 more
wiley   +1 more source

Patient‐reported outcome thresholds and their associations with survival, adverse events, and quality of life in a pooled analysis of breast cancer trials

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The Quality of Life Questionnaire Core 30 (QLQ‐C30) is useful for assessing patient perspectives on the impact of cancer treatments on quality of life. However, thresholds to determine when patients are experiencing functional or symptomatic burdens remain under explored.
Bradley D. Menz   +16 more
wiley   +1 more source

The Fibrosis‐4 score is associated with overall mortality and severe haematological toxicity in older patients with cancer: Analysis of two prospective cohort studies

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Liver function decreases with age, affecting the metabolism of many chemotherapy drugs. For older cancer patients, however, a standardized liver status screening method is lacking. Here, Fibrosis‐4 (FIB‐4) score was investigated for its utility as a non‐invasive method in predicting treatment toxicity and mortality in cancer patients age 70
Victoire de Salins   +14 more
wiley   +1 more source

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