Gene expression profiles of Protein tyrosine phosphatase non-receptor 22, Tumor necrosis factor receptor-associated factor 1 and Interleukin-1 beta in patients with rheumatoid arthritis and healthy controls after severe acute respiratory syndrome-associated coronavirus-2 infection or vaccination. [PDF]
Sanguor MH +4 more
europepmc +1 more source
Abstract Aims The type 1 diabetes population is ageing. Frailty is the age‐related physiological decline that occurs across organ systems, increasing the body's vulnerability to stressors. Current consensus‐based guidelines, derived from evidence in type 2 diabetes, prioritise hypoglycaemia avoidance, which increases falls, hospitalisation and ...
Jonathan A. Golding +5 more
wiley +1 more source
Problem-based learning in traditional Chinese medicine education: current applications and future directions. [PDF]
Jiang N, Li S.
europepmc +1 more source
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas +11 more
wiley +1 more source
Estrogen Stabilizes Interferon-Inducible Genes During Skeletal Muscle Regeneration. [PDF]
Movaghar T, Petereit J, Schneider BSP.
europepmc +1 more source
ABSTRACT Aims There is an unmet need for effective pharmacotherapy for obesity disease management in Japan. Survodutide is a novel glucagon receptor/glucagon‐like peptide‐1 receptor (GLP‐1R) dual agonist with the potential to induce greater weight reductions than GLP‐1R mono‐agonists. We report the design and baseline participant characteristics of the
Koutaro Yokote +10 more
wiley +1 more source
Two geographies, one virus: What recurrent Nipah spillover in India reveals. [PDF]
Patil DY +3 more
europepmc +1 more source
ABSTRACT Aim To evaluate the 12‐month effectiveness and patient persistence of a semaglutide‐supported digital weight‐loss service (DWLS) in a real‐world German cohort. Methods This retrospective study analysed 4535 patients who initiated the Juniper Germany DWLS. Primary endpoints included 12‐month medication and data submission adherence (receiving ≥
Louis Talay +3 more
wiley +1 more source
Serum Activin A Level and 1-Year Mortality in Atrial Septal Defect-Associated Pulmonary Artery Hypertension: A Case-Control Study From the COHARD-PH Registry. [PDF]
Rinastiti P +6 more
europepmc +1 more source
ABSTRACT Background Real‐world data on transfusion needs of patients with myelodysplastic syndromes (MDS), and the impacts of disease‐modifying therapies (DMTs) are sparse. In 2011, 5‐azacitidine became the first funded DMT for MDS and chronic myelomonocytic leukaemia (CMML) patients in Australia and national patient blood management (PBM) guidelines ...
Allison Mo +5 more
wiley +1 more source

