Results 101 to 110 of about 1,377,547 (315)

DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex

open access: yesAdvanced Science, EarlyView.
This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang   +13 more
wiley   +1 more source

Subsidies, Quality, and Regulation in the Nursing Home Industry [PDF]

open access: yes
This paper analyzes the impact of the Medicaid patient subsidy and Certificate of Need (CON) cost containment programs on nursing home behavior.The analysis is complicated by the fact the both proprietary and "not for profit" nursing homes exist, and by ...
Paul J. Gertler
core  

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

open access: yesAdvanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi   +8 more
wiley   +1 more source

Latent profile analysis of nurses’ the quality of palliative nursing care

open access: yesFrontiers in Medicine
ObjectivesTo explore the status of nurses’ the quality of palliative nursing care, analyze the potential characteristics and influencing factors of different types of nurses’ the quality of palliative nursing care, and provide reference for formulating ...
Xue Dong, Yan Liu, Kui Fang, Zezhou Wang
doaj   +1 more source

Student Demographics with Changing Admission Criteria: Is Nursing Diversity at Risk? [PDF]

open access: yes, 2006
Schools of nursing are challenged with choosing from an increasing number of applicants and the need to prepare as many successful nurses as possible to meet the nursing shortage.
Keith, Kimlin McDaniel, Yoon, Jung
core   +1 more source

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

open access: yesAdvanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao   +21 more
wiley   +1 more source

Correlation between ethical sensitivity and humanistic care ability among undergraduate nursing students: a cross-sectional study

open access: yesBMC Nursing
Background In nursing practice, a high level of ethical sensitivity and humanistic care ability must always be maintained. A limited number of studies have investigated the correlation between the level of ethical sensitivity and humanistic care ability ...
Yun Zhang   +6 more
doaj   +1 more source

Subset of nursing diagnoses for the elderly in Primary Health Care [PDF]

open access: diamond, 2016
Jorge Wilker Bezerra Clares   +4 more
openalex   +1 more source

Nursing Informatics: is IT for All Nurses? [PDF]

open access: yes, 2009
Given the definition if nursing informatics it should be a core activity for all nurses, and seen as a tool to support high quality care giving. Three studies reported in this paper show that this is not the case.
Bond, Carol S.   +2 more
core  

Compassion in the emergency department. Part 3: enabling and supporting the delivery of compassionate care [PDF]

open access: yes, 2018
In the final part of this three-part series, David Hunter and colleagues analyse the factors that enable and support delivery of compassionate care in emergency departments (EDs).
Howes, Dora   +2 more
core   +2 more sources

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