Results 51 to 60 of about 261,045 (300)

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li   +12 more
wiley   +1 more source

Nursing and midwifery students’ attitudes towards principles of medical ethics in Kermanshah, Iran

open access: yesBMC Medical Ethics, 2019
Background Professional ethics is one of the important topics, which includes various rights such as respecting the patient’s right to choose (autonomy), being useful (beneficence), being harmless (non- maleficence), and respecting the justice, integrity,
Haleh Jafari   +3 more
doaj   +1 more source

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu   +7 more
wiley   +1 more source

Investigating the Quality of Caring Behaviors of Nurses and Patient Satisfaction in Shahid Beheshti Hospital of Yasuj

open access: yesJournal of Research Development in Nursing and Midwifery, 2016
Background: Caring is the core of Nursing and holistic high-quality care is considered as one of the main concerns of nursing managers. Evaluation by main care recipients and assessment of their satisfaction with different levels of care is a way to ...
Soheila Zabolypour   +4 more
doaj   +2 more sources

Does education increase ethical sensitivity a semi-experimental study

open access: yesScientific Reports
Ethics education plays a crucial role in enhancing the ethical sensitivity of nursing students. This study aimed to assess the impact of an ethics course on the ethical sensitivity levels of nursing students.
Şerife Yılmaz, Gamze Özbek Güven
doaj   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

open access: yesAdvanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li   +10 more
wiley   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

open access: yesAdvanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl   +27 more
wiley   +1 more source

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

open access: yesAdvanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv   +12 more
wiley   +1 more source

Hemşirelerin Deneyimledikleri Ahlaki Sorunlar

open access: yesAnkara Medical Journal, 2018
Giriş: Bu çalışmada amacımız hemşirelerin deneyimledikleri ahlaki sorunları belirlemektir. Materyal ve Metot: Tanımlayıcı ve kesitsel tipteki bu çalışma, 1 Şubat-31 Mayıs 2012 tarihleri arasında Ankara/Türkiye’de özel bir hastanede gerçekleştirilmiştir ...
Fatoş Korkmaz   +2 more
doaj   +1 more source

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