Results 231 to 240 of about 116,732 (322)

Valued Living intervention to increase advance care planning and well‐being in depressed and anxious adults with advanced cancer: Randomized trial in community oncology clinics

open access: yesCancer, Volume 132, Issue 6, 15 March 2026.
Abstract Background Adults with advanced cancer often experience low engagement with advance care planning (ACP) and high levels of depression, anxiety, and fear of death/dying. Access to specialist palliative care is limited. This study tests Valued Living, a novel online acceptance‐based group intervention designed to increase ACP and improve ...
Joanna J. Arch   +8 more
wiley   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

open access: yesPediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar   +8 more
wiley   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello   +10 more
wiley   +1 more source

Accelerating real‐world prediction and research in Alzheimer's: The M3AD study

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Chronic diseases, including Alzheimer's disease (AD) and related dementia (ADRD), do not exist solely as isolated entities. Instead, they weave concomitant trajectories of multiple diseases, conditions, behaviors, and risks, mutually influencing each other's course and natural history, in ways yet unexplored.
Moïse Desvarieux   +37 more
wiley   +1 more source

Integrating real‐world data with gold‐standard longitudinal clinical and genomic data to advance precision medicine for the Alzheimer's Disease Research Center Program and beyond: a proof‐of‐concept data platform

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Integrating real‐world data (RWD) with clinical research datasets creates more complete, context‐rich resources to drive discovery and enable precision medicine in Alzheimer's disease and related dementias. The National Alzheimer's Coordinating Center conducted a proof‐of‐concept (POC) project to link its longitudinal Uniform Data
Sarah Biber   +23 more
wiley   +1 more source

The relationships between ethnoracial identity, Aβ positivity, APOEε4, and medial temporal lobe tau PET

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Clarifying relationships between amyloid, tau, and cognition is crucial to understanding dementia risk, but has been mainly performed in non‐Hispanic White (NHW) participants. It is unknown whether findings are generalizable to other ethnoracial groups.
Koral V. Wheeler   +49 more
wiley   +1 more source

Home - About - Disclaimer - Privacy