Results 121 to 130 of about 1,320,816 (335)

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

open access: yesAdvanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi   +8 more
wiley   +1 more source

Compression the Effect of Clinical Concept Mapping & Nursing Process in Developing Nursing Students’ Critical Thinking Skills [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2012
Introduction: Development of critical thinking and clinical education has remained a serious and considerable challenge throughout the nursing educational system in Iran.
Samereh Abdoli, Tahereh Khajeh Ali
doaj  

Opioid Exposed Mothers and Infants in Delaware: Clinical and Legal Considerations [PDF]

open access: yes, 2016
Drug use is on the rise in Delaware, as demonstrated by the continued increase in infants born with neonatal abstinence syndrome. Thoughful, evidence based, and coordinated approaches are necessary to impact this problem.
Paul, MD, David A.   +1 more
core   +1 more source

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

open access: yesAdvanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao   +21 more
wiley   +1 more source

Pressure Injury and Restraint Prevalence Surveys: Saving Time and Dollars for Patient Care by Automating Manual Chart Abstraction [PDF]

open access: yes, 2019
Bronson Healthcare Group performs quarterly pressure injury and restraint audits as part of the National Database of Nursing Quality Indicators (NDNQI).
Bush, Shellie   +4 more
core   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li   +12 more
wiley   +1 more source

Problems in treatment of children with burns on the basis of ICNP® - case report

open access: yesJournal of Education, Health and Sport, 2019
Admission. Burn damage to the skin, mucosa, as well as tissues located deeper by the heat supplied from the outside. Thermal trauma is one of the most common reasons for reporting a child under 6 years of age to Hospital Emergency Departments.
Eleonora Anna Mess   +2 more
doaj  

The production and deployment of an on-line video learning bank in a skills training environment [PDF]

open access: yes, 2009
This paper describes the introduction of videos as aids in clinical skills teaching. Although the process explored focuses on a nursing clinical skills environment it is relevant to many other disciplines.
Cannon, Gerald   +3 more
core   +1 more source

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

open access: yesAdvanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He   +13 more
wiley   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello   +10 more
wiley   +1 more source

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