Results 51 to 60 of about 113,622 (313)

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source

EXPERIENCIANDO UM MARCO CONCEITUAL PARA O CUIDADO EM ENFERMAGEM AO SER-FAMILIAR E/OU CUIDADOR E AO SER-CRIANÇA

Cogitare Enfermagem, 2003
Este artigo apresenta o marco conceitual construído a partir da prática experienciada em Enfermagem Pediátrica, buscando o aprimoramento do encontro vivido e dialogado de cuidado ao ser-familiar e/ou cuidador e ao ser-criança no mundo da vida do hospital.
Diego Schaurich, Stela Maris de Mello Padoin, Maria da Graça Corso da Motta   +2 more
doaj   +1 more source

Application of Nursing Intervention Plan Based on Symptom Management Theory among Breast Cancer Patients [PDF]

, 2022
Qingqing Xu, Yu Chen, Xiaping Shen, Qunying Fang   +3 more
openalex   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

La teoría Déficit de autocuidado: Dorothea Elizabeth Orem

Gaceta Médica Espirituana, 2017
Fundamento: Dorothea E. Orem presenta su teoría del déficit de autocuidado como una teoría general compuesta por tres teorías relacionadas entre sí: Teoría de autocuidado, teoría del déficit autocuidado y la teoría de los sistemas de Enfermería ...
Ydalsys Naranjo Hernández, José Alejandro Concepción Pacheco, Miriam Rodríguez Larreynaga   +2 more
doaj  

Factors Affecting Condom-Use Behaviors Among Female Emerging Adults in South Korea

Psychology Research and Behavior Management, 2022
Jungmin Lee School of Nursing, Hallym University, Chuncheon-si, Gangwon-do, South KoreaCorrespondence: Jungmin Lee, Tel +82-33-248-2710, Fax +82-33-248-2734, Email j_lee0624@hallym.ac.krPurpose: To date, no studies have examined the association between ...
Lee J
doaj  

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

Do Consumers Value Diversity in Agriculture? A Choice Experiment

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Farm ownership in the US today is racially and ethnically homogeneous. Diverse farmers and ranchers make up less than 10% of all producers, they tend to be less financially stable and have tighter profit margins. In the past few years, both government and industry programs have aimed to increase the participation and profitability of diverse ...
Maria Kalaitzandonakes, Jared P. Hutchins, Gerald Mashange   +2 more
wiley   +1 more source

Regional Differences in U.S. Consumer Preferences for Native Woody Shrubs With Varying Aesthetic Characteristics

Agribusiness, EarlyView.
ABSTRACT Native plants offer a variety of aesthetic (e.g., fall colour, fruit, flowers) and functional benefits (e.g., pollinator friendly, wildlife friendly, water management). How these benefits influence consumer choice and perceived value of native versus introduced plants is not well understood.
Alicia Rihn, Ariana P. Torres, Sue Barton, Bridget K. Behe   +3 more
wiley   +1 more source