Results 81 to 90 of about 2,061,205 (256)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Contribution of corn intercropped with Brachiaria species to nutrient cycling

open access: yesPesquisa Agropecuária Tropical, 2019
The corn biomass and nutrient dynamics may be altered when it is intercropped with Brachiaria (syn. Urochloa spp.). The present study aimed to investigate the dynamics of biomass, nitrogen (N), phosphorus (P) and potassium (K) for farming systems that ...
Silas Maciel de Oliveira   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

A new framework of measuring national nutrients balance for international and global comparison [PDF]

open access: yes
Nutrients balance such as nitrogen and phosphorus balance are increasingly used as an indicator of the environmental performance of agricultural sector in international and global context.
Viet-Ngu Hoang, Mohammad Alauddin
core  

Effects of long-term chemical fertilization on trends of rice yield and nutrient use efficiency under double rice cultivation in subtropical China

open access: yesPlant, Soil and Environment, 2014
A long-term (33 years) experiments were conducted to investigate the effect of chemical fertilization on rice yield, yield trends, soil properties, agronomic efficiency of applied nutrients and nutrient balance for the double rice cropping systems in ...
L. Bi, J. Xia, K. Liu, D. Li, X. Yu
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

MEASUREMENT OF AGRICULTURAL TOTAL FACTOR PRODUCTIVITY GROWTH INCORPORATING ENVIRONMENTAL FACTORS: A NUTRIENTS BALANCE APPROACH [PDF]

open access: yes
This paper develops a new measure of total factor productivity growth in agricultural production which incorporates environmental effects. The new measure is called the Total Factor Nutrient-Orientated Productivity (TFNP) Index, and incorporates a ...
Coelli, Tim J., Hoang, Viet-Ngu
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

An Evaluation of comparative effects of feeding synthetic and herbal choline on broiler performance, nutrient balance and serum activities [PDF]

open access: yesVeterinary World, 2008
An experiment in broiler chickens was conducted to evaluate comparative efficacy of herbal and synthetic choline on body weight, weight gain, FCR, nutrient balance serum activities and economic benefit for 35 days on deep litter. A significant (P<0.05)
Jadhav N. V.   +2 more
doaj  

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