G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Optimizing nutrient management for Kodo millet (Paspalum scrobiculatum L.) in the Alfisols of Southern India through modeling soil, plant, and fertilizer interactions. [PDF]
Rangaiah KM +8 more
europepmc +1 more source
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao +14 more
wiley +1 more source
Using science communication research to practice iterative engagement in collaborative nutrient management. [PDF]
Canfield K, Chatelain C.
europepmc +1 more source
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang +6 more
wiley +1 more source
Ribosomal RNA operon copy number: A trait‐informed framework to close the microbial cultivation gap
Yuxiao Huang +8 more
doaj +1 more source
"Harnessing the power of soil microbes: Their dual impact in integrated nutrient management and mediating climate stress for sustainable rice crop production" A systematic review. [PDF]
Marzouk SH +3 more
europepmc +1 more source
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi +3 more
wiley +1 more source
Yield gap reduction of pineapple (Ananas comosus L.) by site-specific nutrient management. [PDF]
Khuong NQ +3 more
europepmc +1 more source
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu +9 more
wiley +1 more source

