Results 81 to 90 of about 713,334 (308)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

A BIOTIC CONTROL PERSPECTIVE ON NITRATE CONTAMINATION OF GROUNDWATER FROM AGRICULTURAL PRODUCTION [PDF]

Agronomists consider the continuity and nutrient capturing properties of cover crops as important determinants of nutrient cycling in agricultural systems.
Erickson, Jon D., Schlapfer, Felix
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Organic farming significantly improves microbial community structure, network complexity, and functional diversity in the Gannan navel orange orchard

BMC Microbiology
Background In recent years, improper agricultural management practices have led to the loss of biodiversity and poor fruit quality in orchards. Converting conventional farming to organic farming is an environmentally responsible approach to improving ...
Lianlian Liu, Muhammad Atif Muneer, Yanting Zhong, Boyi He, Xuexian Li   +4 more
doaj   +1 more source

From Nanomaterials to Nanofertilizers: Applications, Ecological Risks, and Prospects for Sustainable Agriculture

Plants
Nanofertilizers have attracted increasing attention as an approach to improve the low nutrient use efficiency of conventional fertilizers, in which only a limited fraction of applied nitrogen, phosphorus, and potassium is ultimately taken up by crops ...
Jingyi Zhang, Taiming Zhang, Yukui Rui
doaj   +1 more source

Fundamentals of Nutrient Management: Why Nutrient Replacement is Essential in Organic and all Agriculture [PDF]

, 2008
There is a belief, going back to the foundation of organic agriculture, that nutrient replacement, i.e., the use of ‘fertilisers’, within organic agriculture is not required.
Merfield, Charles
core  

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

easynem: An R package for computing and visualizing soil nematode ecological indices

iMetaOmics
The contribution of soil nematode communities to soil health and ecological functions has attracted increasing attention. To support this research, we developed an R package easynem, which enables convenient calculation of nematode ecological indices and
Kunguang Wang, Jiqi Shao, Jing Ma, Dongming Cui, Ziyue Fu, Lan Tang, Runjiao Ma, Yuanmei Zuo, Shaohua Gu   +8 more
doaj   +1 more source

Integrated Transcriptomic and Metabolomic Analyses Shed Light on the Regulation of Aromatic Amino Acid Biosynthesis in a Novel Albino Tea (Camellia sinensis) Mutation

Current Issues in Molecular Biology
Off-white or yellowish shoots are common in tea plants (Camellia sinensis L.), and such albino variations are often accompanied by metabolic reprogramming, including increased contents of amino acids and lower levels of polyphenols.
Ying Gao, Suimei Li, Xiaojia Zhang, Shuwei Yu, Xinyu Liu, Changbo Yuan, Yuantao Yao, Fan’an Zhang, Lubin Song   +8 more
doaj   +1 more source

NY Pollution Discharge Elimination Permits for CAFOs, Management Adjustments and the Environment [PDF]

Weakening demand for livestock and dairy produce, historically high prices for feed ingredients and increasingly strict regulations on animal waste management continue to put significant pressure on livestock and dairy operating margins.
Boisvert, Richard N., Enahoro, Dolapo K., Schmit, Todd M.   +2 more
core   +1 more source