Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
The Importance of Nutrition in Neurological Disorders and Nutrition Assessment Methods. [PDF]
Brain Neurorehabil, 2022 Lee H.
europepmc +1 more source
The link between poverty and malnutrition : a household theoretic approach [PDF]
Past studies have identified nutrition exclusively with nutrient intake. A better definition of nutrition would critically affect the link between poverty and malnutrition and would affect the implications for policies designed to improve the nutritional
Schiff, Maurice, Valdes, Alberto
core
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Nutrition Assessment and Dietary Interventions in Heart Failure: JACC Review Topic of the Week. [PDF]
J Am Coll Cardiol, 2022 Driggin E +7 more
europepmc +1 more source
Instrumental Variable Estimation of the Causal Effect of Hunger Early in Life on Health Later in Life [PDF]
Numerous studies have evaluated the effect of nutrition early in life on health much later in life by comparing individuals born during a famine to others.
Pinger, Pia +2 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Current Insights in Nutrition Assessment and Intervention for Malnutrition or Muscle Loss in People with Lung Cancer: A Narrative Review. [PDF]
Adv Nutr, 2022 Kiss N, Curtis A.
europepmc +1 more source
An Assessment of Health Disparities among a Community Sample of LGBQ College Students [PDF]
, 2018 Lesbian, gay, bisexual, and queer (LGBQ) individuals are a marginalized population in the United States, and this status places them at a greater risk for adverse health outcomes, such as tobacco and substance use, obesity, cancer, sexually-transmitted ...
Benotsch, Eric +2 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source