Results 21 to 30 of about 291,961 (241)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The effect of maternal near miss on adverse infant nutritional outcomes

Clinics
OBJECTIVES: To evaluate the association between self-reported maternal near miss and adverse nutritional status in children under one year of age. METHODS: This study is a secondary analysis of a study in which women who took their children under one ...
Dulce M. Zanardi, Erly C. Moura, Leonor P. Santos, Maria C. Leal, Jose G. Cecatti   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Assessment of colonoscopy screening by elderly people

Journal of Education, Health and Sport, 2017
Forecasts indicate that in the next decade cancer will become the most common cause of death in our country. Over 140,000 new cases of malignant neoplasms are reported annually in Poland.
Piotr Sikorski, Małgorzata Szamocka, Agnieszka Meder, Monika Anna Ameryk, Maciej Świątkowski   +4 more
doaj   +3 more sources

Transitioning to digital first line intervention – validation of a brief online screener for early identification of a suspected eating disorder: study protocol

Journal of Eating Disorders, 2020
Background Only one in four people with eating disorders seeks treatment, and of those who do seek treatment, 20% go on to experience a chronic course.
Emma Bryant, Jane Miskovic-Wheatley, Stephen Touyz, Ross D. Crosby, Eyza Koreshe, Li Cao, Sarah Maguire   +6 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Nutritional status, swallowing disorders, and respiratory prognosis in adult Duchenne muscular dystrophy patients [PDF]

, 2021
Abdallah Fayssoil, Cendrine Chaffaut, Hélène Prigent, Pascal Laforêt, Bernard Clair, David Orlikowski, Adam Ogna, Sylvie Chevret, Paris Meng, Djillali Annane, Frédéric Lofaso, Pascal Crenn   +11 more
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source