Results 91 to 100 of about 783,447 (313)

Using the promoters of MerR family proteins as “rheostats” to engineer whole-cell heavy metal biosensors with adjustable sensitivity

Journal of Biological Engineering, 2019
Background Whole cell biosensors provide a simple method for the detection of heavy metals. However, previous designs of them rely primarily on simulation of heavy metal resistance systems of bacteria.
Mingzhang Guo, Ruoxi Du, Zixin Xie, Xiaoyun He, Kunlun Huang, Yunbo Luo, Wentao Xu   +6 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Integrated transcriptomics and metabolomics reveal the mechanism of intestinal damage upon acute patulin exposure in mice

Ecotoxicology and Environmental Safety
Mycotoxin contamination has become a major food safety issue and greatly threatens human and animal health. Patulin (PAT), a common mycotoxin in the environment, is exposed through the food chain and damages the gastrointestinal tract.
Ting Zhang, Min Yan, Min Chang, Xiaohui Hou, Furong Wang, Wei Song, Yuan Wang, Kewei Feng, Yahong Yuan, Tianli Yue   +9 more
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Dietary factors and Type 2 diabetes in the Middle East : what is the evidence for an association? - A systematic review. [PDF]

, 2013
This review aims to search and summarise the available evidence on the association between dietary factors and type 2 diabetes mellitus (T2DM) in Middle Eastern populations, where diabetes prevalence is among the highest in the world.
AI-Othaimeen, Al-Shoshan, Alrabadi, Amini, Azadbakht, Baxter, Brunner, Colditz, Esmaillzadeh, Fung, Gross, Halton, Karen Rees, Khani, Lena Al-Khudairy, McKeown, Midhet, Musaiger, Nasser Al-Daghri, Ng, Ramachandran, Sarrafzadegan, Saverio Stranges, Schulze, Shaw, Sudhesh Kumar, Willett, Willett   +27 more
core   +2 more sources

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

peu-MIR2916-p3-enriched garlic exosomes ameliorate murine colitis by reshaping gut microbiota, especially by boosting the anti-colitic Bacteroides thetaiotaomicron

Pharmacological Research
Plant-derived exosome-like nanoparticles (ELNs) have drawn considerable attention for oral treatment of colonic diseases. However, the roles of ELNs derived from garlic on colitis remain unclear.
Xiaoyuan Wang, Yueyue Liu, Xinyue Dong, Tianchi Duan, Chennan Wang, Lu Wang, Xingbin Yang, Honglei Tian, Ting Li   +8 more
doaj   +1 more source

Equine nutrition: a preliminary investigation of feeding practices in equine veterinary hospitals in the USA [PDF]

, 2018
Nutrition plays an important role in equine rehabilitation, with contradictory approaches existing on correct nutritional management of patients. The preponderance of information related to nutrient requirements for horses was designed for healthy ...
Garber, Anna, Hastie, Peter, Kaya Karasu, Gulsah, Murray, Jo-Anne, Park, Katarina, Robert, Jayne   +5 more
core  

Dietary patterns for adults with chronic kidney disease [PDF]

, 2015
This is the protocol for a review and there is no abstract. The objectives are as follows: This review will evaluate the benefits and harms of dietary patterns among adults with CKD (any stage including people with end-stage kidney disease (ESKD) treated
Campbell, Katrina Louise, Craig, Jonathan C, Johnson, David W, Maggo, Jasjot K, Palmer, Suetonia C, Ruospo, Marinella, Strippoli, Giovanni F M, Sutanto, Bernadet, Tong, Allison   +8 more
core   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source