Results 131 to 140 of about 783,447 (313)

Assessment of knowledge and nutritional status of students before and after nutritional education

open access: yesRoczniki Panstwowego Zakladu Higieny
Introduction There are many educational and health programs implemented on a smaller or larger scale in Poland. Many of them address the problem of overweight and obesity in different age groups.
Joanna Wyka   +6 more
doaj   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

A Fluorescent Aptasensor Based on Tb-MOFs and Its Application for the Detection of Pseudomonas aeruginosa in Foods

open access: yesFoods
Pseudomonas aeruginosa is an important waterborne pathogen that is harmful to food safety and human health. Therefore, the detection of Pseudomonas aeruginosa has become an essential item in food sampling.
Jinqiong Xu   +3 more
doaj   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

open access: yesAdvanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang   +17 more
wiley   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

open access: yesAdvanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao   +17 more
wiley   +1 more source

Identification of key quality indicators for Zigui navel orange varieties through multivariate analyses

open access: yesFood Chemistry: X
This study comprehensively characterized five representative Zigui navel orange cultivars regarding physicochemical properties, bioactive compounds, and volatiles.
Mingfang Tao   +8 more
doaj   +1 more source

Agroforestry, food and nutritional security [PDF]

open access: yes, 2013
Agroforestry supports food and nutritional security through : (1) the direct provision of tree food s such as fruit s and leaf y vegetables and by supporting staple crop production ; (2) by raising farmers' incomes through the sale of tree products and ...
Dawson, Ian   +9 more
core  

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Unveiling sex-specific cardiometabolic and adiposity risk profiles for precision prevention

open access: yesEuropean Journal of Medical Research
Introduction Cardiometabolic diseases (CMDs) are the leading global cause of mortality, driven by interrelated metabolic and cardiovascular factors. Sex differences significantly shape risk.
Gianvincenzo Zuccotti   +16 more
doaj   +1 more source

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