XChrom is a deep learning framework that integrates genomic sequence and single‐cell context to predict chromatin accessibility. It generalizes to unseen cells and genomic regions, enabling cross‐sample and cross‐species analysis. Applied to COVID‐19 patient data, XChrom reveals key transcriptional regulatory mechanisms and disease‐associated ...
Yuanyuan Miao +5 more
wiley +1 more source
Dietary Inulin Modulates Intestinal Health and Muscle Nutritional Composition in Juvenile Silver Pomfret (<i>Pampus argenteus</i>). [PDF]
Zhang C +8 more
europepmc +1 more source
Hydrodynamic Selection of Polymorphic Assembly Pathways in Plant Protein Amyloid Fibrils
Hydrodynamic conditions are revealed to govern polymorphic assembly of soy protein amyloid fibrils. Distinct flow‐induced drafting, kissing, and docking dynamics direct fibril growth into multiple morphologies, linking fluid mechanics with nanoscale assembly and enabling rational design of functional amyloid materials.
Zejian Xu +8 more
wiley +1 more source
Camel Milk as a Functional Food: Nutritional Composition, Health-Promoting Benefits, and Safety Considerations. [PDF]
Bereda G, Uthirapathy S, Ahamad J.
europepmc +1 more source
Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng +4 more
wiley +1 more source
Nutritional Composition, Chemical Safety, and Microbiological Quality of Farmed Palm Weevil Larvae (<i>Rhynchophorus phoenicis</i>) From a Commercial Rearing Unit in Ghana. [PDF]
Mintah BK +6 more
europepmc +1 more source
NUB1 Regulates Muscle Atrophy in Lung Cancer Cachexia via NF‐κB Signaling Pathway
ABSTRACT Cancer‐associated cachexia (CAC) is a devastating multifactorial syndrome characterized by progressive skeletal muscle atrophy. Its mechanisms remain incompletely clarified, with limited effective therapeutic targets. NUB1, a negative regulator of ubiquitin‐like proteins mediating protein degradation, has not been fully elucidated in CAC ...
Yuqi Han +13 more
wiley +1 more source
Comprehensive Evaluation of Agronomic Traits and Nutritional Composition in Summer-Sown Vegetable Soybean Varieties from Shanghai, China. [PDF]
Cao B +8 more
europepmc +1 more source

