Results 181 to 190 of about 10,826,082 (381)
This study reveals that specific genetic variations in gut‐residing Saccharomyces cerevisiae significantly extend healthspan and lifespan in Drosophila melanogaster. These mutants rejuvenate aged intestinal metabolism, upregulate mitochondrial proteins, and enhance energy pathways.
Liying Wang+11 more
wiley +1 more source
INFLUENCE OF SELENIUM ON THE SELENIUM CONTENTS OF HAIR AND ON THE INCIDENCE OF NUTRITIONAL MUSCULAR DISEASE IN BEEF CATTLE [PDF]
M. Hidiroglou, R. B. Carson, G. Brossard
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This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen+7 more
wiley +1 more source
The “Yes” and “No” of Nutrition and Natural Resistance to Infectious Disease
Howard A. Schneider
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1) 14, 15‐EET levels were decreased in ovarian granulosa cells, follicular fluid, peritoneal fluid from endometriosis patients. 2) EETs reduction in endometriosis follicular fluid aggravated granulosa cell senescence. 3) ROS reduced 14, 15‐EET levels by upregulating EPHX2 through a mechanism involving histone methylation modification.
Xiang Lin+11 more
wiley +1 more source
This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin+7 more
wiley +1 more source
Protein Metabolism. Influence of Growth Hormone, Anabolic Steroids, and Nutrition in Health and Disease. An International Symposium, Leyden, 25th-29th June, 1962 [PDF]
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