Results 161 to 170 of about 6,752,604 (302)

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

open access: yesAdvanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang   +13 more
wiley   +1 more source

Construction of a nutritional risk prediction model for ovarian cancer patients based on Logistic regression and decision tree

open access: yesHuli yanjiu
ObjectiveTo construct a nutritional risk prediction model for ovarian cancer patients based on logistic regression and classification and regression tree(CART).MethodsA total of 326 ovarian cancer patients admitted to the oncology department of a ...
WANG Jing   +5 more
doaj  

Intermittent Fasting Reduces Taurine Availability and Promotes Antitumor Immunity Through PERK Attenuation‐Associated Paraptosis‐Like Cell Death in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies reduced taurine availability as a mediator of intermittent fasting in colorectal cancer and shows that taurine interacts with GRP78 to maintain PERK abundance post‐transcriptionally. It further shows that taurine depletion destabilizes PERK, induces immunogenic paraptosis, remodels the tumor microenvironment toward a CD8+ T cell ...
Baohui Song   +11 more
wiley   +1 more source

An alternative short-form Mini-Nutritional Assessment for rating the risk of malnutrition in persons on haemodialysis

open access: yes, 2013
[[abstract]]AIMS AND OBJECTIVES: To improve the short-form Mini-Nutritional Assessment (MNA) to ameliorate under-rating the risk of malnutrition in patients on haemodialysis.
蔡仲弘;Alan, C.Tsai;Chang, TL;Chang, TL;Chang, Mei-Zu;Chang, Mei-Zu
core  

Comparison of application value of mNUTRIC and NRS⁃2002 in prognosis evaluation of critically ill patients

open access: yesHuli yanjiu
ObjectiveTo evaluate the nutritional risk of patients in emergency intensive care unit (EICU) using mNUTRIC score and NRS-2002, and to compare the value of the two tools in assessing 28-day mortalityMethodsPatients admitted to the EICU from February to ...
WANG Lingli   +5 more
doaj  

Porphyrin‐Based Porous Materials for Antibacterial Applications

open access: yesAdvanced Science, EarlyView.
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang   +4 more
wiley   +1 more source

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao   +12 more
wiley   +1 more source

CRISPR‐Scan: Cas13a Mismatch Tolerance Enabled Ultra‐Multiplexed Detection of Same‐Site Indels in Acute Myeloid Leukemia

open access: yesAdvanced Science, EarlyView.
Accurately detecting diverse same‐locus insertions or deletions (indels) remains challenging. This study reveals the mismatch‐tolerance profile of LwaCas13a and establishes CRISPR‐Scan, which uses a single crRNA to detect multiple same‐locus indels. The one‐pot assay detects nucleophosmin 1 (NPM1) mutant allele frequencies down to 0.01%, agrees with ...
Linlin Bai   +13 more
wiley   +1 more source

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