Results 241 to 250 of about 10,198,424 (331)

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Evaluating the effect of nutritional support in geriatric inpatients classified by the GLIM criteria. [PDF]

J Nutr Health Aging
Jiang S, Chen X, Ma L, Guo Q, Luo L, Wang Y, Qu X, Li J, An L, Huang W, Wu Y, Zhang H, Zhang C, Fan Y, Zheng S, Cao J, Liu X.   +16 more
europepmc   +1 more source

Nutrition support for HIV-TB co-infected adults in Senegal, West Africa: A randomized pilot implementation study

, 2019
Noelle A. Benzekri, Jacques F. Sambou, Ibrahima Tito Tamba, Jean Philippe Diatta, Ibrahima Sall, Ousseynou Cisse, Makhtar Thiam, Gaetan Bassene, Ndeye Maguette Badji, Khadim Faye, Fatima Sall, Jean Jacques Malomar, Moussa Seydi, Geoffrey S. Gottlieb   +13 more
openalex   +2 more sources

Iron/Cobalt Dual‐Atom Catalyst Orchestrate Photothermal‐Chemodynamic Immunotherapy Against MRSA: Multi‐Omics Dissection in Murine and Porcine Models

Advanced Science, EarlyView.
FeCo dual‐atom catalyst (FeCo‐N‐DAC) with ultrahigh metal loading (Fe > 5.4%, Co > 4.8%) is developed for synergistic photothermal‐chemodynamic immunotherapy. FeCo‐N‐DAC penetrates deep‐seated tissues, eradicates MRSA biofilms, and reprograms immune‐inflammatory pathways via multi‐omics‐validated mechanisms.
Shihao Xu, Binge Huang, Hao Lin, Jinming Li, Zhaoxiang Lu, Qi Zhang, Jia Li, Shiping Yang, Songsong Lan, Yan Yang, Yun Feng, Xiaojun He   +11 more
wiley   +1 more source

Effect of a nursing intervention based on nutritional support on biochemical parameters and quality of life in patients with hyperthyroidism combined with diabetes mellitus. [PDF]

Front Endocrinol (Lausanne)
Yang H, Feng J.
europepmc   +1 more source

TOPK Inhibition Promotes Anti‐Tumor Immunity Via eIF4F Complex Mediated STAT1 Translation in Gastric Cancer

Advanced Science, EarlyView.
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen, Longtao Huangfu, Gangjian Wang, Xueying Wang, Huanbo Zhu, Qian Yao, Cong Chen, Xiaohuan Tang, Ting Guo, Biao Fan, Xingyang Liu, Qingda Li, Zining Liu, Ying Hu, Tianze Sun, Jiafu Ji, Xiaofang Xing   +16 more
wiley   +1 more source

PERIOPERATIVE NUTRITIONAL SUPPORT IN GASTROINTESTINAL SURGERY - WHY IS IT ESSENTIAL? [PDF]

Arq Gastroenterol
Magro DO, Lima AP, Coy CSR, Kotze PG.
europepmc   +1 more source

Gender Differences in Feeding, Care, Support and Nutritional Status of Children in the Rural Area of Kaski District, Nepal.

, 2019
Basundhara Shrestha, Dipendra Kumar Yadav   +1 more
openalex   +2 more sources

Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat

Advanced Science, EarlyView.
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. ‌Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang, Huanyu Wang, Qianqian Kang, Ruping Pan, Rui He, Min Yang, Jiadai Liu, Xuemin Peng, Yuyu Xie, Hongyan Deng, Wenshe Wang, Zengzhe Zhu, Jing Ge, Yulian Liu, Ronghui Gao, Yaming Guo, Peng Yu, Limeng Pan, Danpei Li, Pema Maretich, Xiaoping Luo, Xuefeng Yu, Yong Chen   +22 more
wiley   +1 more source

Therapeutic Effect of Arginine, Glutamine and β-Hydroxy β-Methyl Butyrate Mixture as Nutritional Support on DSS-Induced Ulcerative Colitis in Rats. [PDF]

Nutrients
Yılmaz Akyüz E, Akyüz C, Yenilmez Tunoglu EN, Dogan M, Bayram B, Tutar Y.   +5 more
europepmc   +1 more source