Results 251 to 260 of about 9,610,331 (363)

GHSR‐Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation

open access: yesAdvanced Science, EarlyView.
Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim   +9 more
wiley   +1 more source

Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation

open access: yesAdvanced Science, EarlyView.
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu   +8 more
wiley   +1 more source

Single‐Cell Transcriptome Reveals Aquaporin‐Mediated Carbon Nanosol‐Induced Growth Promotion of Plants

open access: yesAdvanced Science, EarlyView.
Carbon nanosol (CNS) exhibits rapid root penetration capacity, enhancing plant growth through boosting stomatal density and antioxidative enzyme activity. Single‐cell transcriptomic profiling uncovers cell type‐specific gene expression patterns and developmental trajectories during CNS‐mediated growth promotion.
Lingtong Cheng   +10 more
wiley   +1 more source

Nutritional Support Reduces Circulating Cytokines in Patients with Heart Failure. [PDF]

open access: yesNutrients
Herrera-Martínez AD   +9 more
europepmc   +1 more source

A Generative AI‐Assisted Piezo‐MEMS Ultrasound Device for Plant Dehydration Monitoring

open access: yesAdvanced Science, EarlyView.
This study introduces a complementary metal–oxide–semiconductor (CMOS)‐compatible wearable piezoelectric micromachined ultrasound transducers (PMUTs) that sandwiches the leaf (PMUT–Leaf–PMUT, PLP) and employs generative artificial intelligence for real‐time analysis.
Kaustav Roy   +7 more
wiley   +1 more source

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