Results 141 to 150 of about 32,590 (283)
XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss
Advanced Science, EarlyView.Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan +13 more
wiley +1 more source
ESTIMATING CONSUMER WILLINGNESS-TO-PAY FOR COUNTRY OF-ORIGIN-LABELS FOR BEEF PRODUCTS [PDF]
Country-of-origin labeling is now being considered as an alternative by the U.S. Senate. Research is still needed to determine what attributes consumers value in domestic versus imported beef, and to quantify the value that consumers place on country-of ...
Loureiro, Maria L., Umberger, Wendy J.
core +1 more source
Advanced Science, EarlyView.Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao +36 more
wiley +1 more source
Nutrición Hospitalaria, 2009 Introducción: La adolescencia se considera un periodo crítico en la adquisición y configuración de hábitos alimentarios y de un estilo de vida saludable para el futuro joven y que probablemente serán perdurables en la edad adulta. La obesidad infantil y juvenil es un problema de Salud Pública cuyo control pasa necesariamente por la prevención y la ...
M.ª I. Martínez +5 more
openaire +1 more source
FACTORS INFLUENCING CONSUMER DECISIONS RELATED TO "NATURAL" BEEF IN THE SOUTHERN PLAINS [PDF]
Consumer/Household Economics,
Goss, Jody +2 more
core +1 more source
Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis
Advanced Science, EarlyView.Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu +13 more
wiley +1 more source
Nutrición Hospitalaria, 2010 Introducción: El trasplante renopancreático es en la actualidad el tratamiento elegido para los pacientes diabéticos tipo 1 con ERD avanzada. Estudios científicos sobre los beneficios de esta terapéutica avalan la aceptación de la misma como lo más ...
M.ª L. Iglesias +5 more
doaj
Advanced Science, EarlyView.Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim +7 more
wiley +1 more source
Waterfowl Harvest Benefits in Northern Aboriginal Communities and Potential Climate Change Impacts [PDF]
Migratory waterfowl are important to the diets of residents in Canada’s northern communities. Contrary to recreational hunters, indigenous peoples have rights to harvest wildlife for subsistence needs without permits. As a result, migratory waterfowl are
Ann Chan-McLeod +2 more
core
Advanced Science, EarlyView.This study reveals the mechanism by which jasmonic acid (JA) regulates lycopene synthesis under light and dark conditions. In light, JA activates SlMYC2, which suppresses SlPIF1a and promotes SlPSY1 expression. In darkness, JA induces the acetyltransferase SlNATA1, which acetylates the dark‐accumulated SlPIF1a, thereby repressing SlPSY1 expression ...
Jiayi Xu +10 more
wiley +1 more source