Results 51 to 60 of about 741,228 (286)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Cuestionario de calidad de vida relacionado con el estado nutricional (CaVEN) Quality of life questionnaire related to nutritional status

open access: yesNutrición Hospitalaria, 2012
Objetivo: Construir y validar un instrumento para medir la calidad de vida percibida en relación con el estado nutricional. Material y método: Mediante grupos focales y entrevistas con expertos en nutrición se identificaron las dimensiones con mayor ...
C. Wanden-Berghe   +4 more
doaj  

Farmers’ valuation of transgenic biofortified sorghum for nutritional improvement in Burkina Faso: A latent class approach

open access: yesFood Policy, 2018
Abstract Micronutrient malnutrition has been a challenge in Burkina Faso for many years, where it has led to worsening food security situation. Vitamin, iron and zinc deficiencies affects 1 in 4 persons in the country and is responsible for early child nutritional disorder.
Obi Chinedu   +5 more
openaire   +2 more sources

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The value of near-infrared spectroscopy: using nutritional information of soybean meals by country of origin in feed formulation

open access: yesJournal of Applied Poultry Research
SUMMARY: Feedstuff variability negatively affects the poultry production chain. The nutritional value of soybean meal (SBM) is variable, especially among countries of origin.
T.H. Yabuta, E.O. Oviedo-Rondón
doaj   +1 more source

Prevalence and social determinants of malnutrition in children under 5 years affiliated to the SISBEN of the urban area of the municipality of Palermo in Colombia, 2017

open access: yesUniversidad y Salud, 2018
Introduction: Malnutrition includes undernourishment, overweight and obesity generated by food imbalance and the presence of social determinants of health (SDH) that mainly affects the child population.
Nathaly Barrera-Dussán   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Bridging the Quality-Price Gap: Unlocking Consumer Premiums for High-Quality Rice in China

open access: yesFoods
The transition of global agriculture from yield-driven production to quality-driven systems has gained urgency, where premium pricing strategies offer pathways to enhance farmer incomes and promote sustainable practices.
Yiyuan Miao   +4 more
doaj   +1 more source

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