Results 91 to 100 of about 209,152 (323)

High‐Content SRS Imaging Unveils Altered Cholesterol Metabolism in Ovarian Cancers Under CAR‐T Treatment

Advanced Science, EarlyView.
High‐content Stimulated Raman Scattering (SRS) Imaging reveals that ovarian cancer cells surviving Chimeric Antigen Receptor (CAR) ‐T cell challenge exhibit increased cholesterol esterification. Pharmacological inhibition of this pathway with Avasimibe significantly enhances CAR‐T induced killing of ovarian cancer cells by reducing cancer cell ...
Chinmayee V. Prabhu Dessai, Zhuoying Huang, Haonan Lin, Guangrui Ding, Hongjian He, Menna Siddiqui, Meng Zhang, Wilson Wong, Ji‐Xin Cheng   +8 more
wiley   +1 more source

An INTRODUCTION TO CUDA Programming [PDF]

The graphics boards have become so powerful that they are usded for mathematical computations, such as matrix multiplication and transposition, which are required for complex visual and physics simulations in computer games.
Irina Mocanu
core  

vEMRec: High‐Resolution Volume Electron Microscopy Reconstruction Based on Structure‐Preserving and High‐Fidelity 3D Alignment

Advanced Science, EarlyView.
vEMRec is a frequency‐adaptive computational framework for three‐dimensional alignment in volume electron microscopy. It integrates feature‐based rigid alignment with Gaussian filter‐guided elastic registration to correct rigid misalignments and nonlinear distortions while preserving structural fidelity.
Zhenbang Zhang, Hongjia Li, Zhongjun Yang, Zhiqiang Xu, Duanchen Sun, Xin Gao, Fa Zhang, Renmin Han   +7 more
wiley   +1 more source

Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI

Advanced Science, EarlyView.
ABSTRACT 2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time‐consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal
Pablo Arratia, Martin J. Graves, Mary McLean, Carolin Pirkl, Carola‐Bibiane Schönlieb, Timo Schirmer, Florian Wiesinger, Matthias J. Ehrhardt   +7 more
wiley   +1 more source

CondensNet: enabling stable long-term climate simulations via hybrid deep learning models with adaptive physical constraints

npj Climate and Atmospheric Science
Accurate and efficient climate simulations are crucial for understanding Earth’s evolving climate. However, current general circulation models (GCMs) face challenges in capturing unresolved physical processes, such as cloud and convection.
Xin Wang, Jianda Chen, Juntao Yang, Jeff Adie, Simon See, Kalli Furtado, Chen Chen, Troy Arcomano, Romit Maulik, Wei Xue, Gianmarco Mengaldo   +10 more
doaj   +1 more source

Quantum simulation of CO2 chemisorption in an amine-functionalized metal–organic framework [PDF]

AIP Advances
We perform a series of calculations using simulated quantum processing units (QPUs), accelerated by the NVIDIA CUDA-Q platform, focusing on a molecular analog of an amine-functionalized metal–organic framework, a promising class of materials for CO2 ...
Jonathan R. Owens, Marwa H. Farag, Pooja Rao, Annarita Giani   +3 more
doaj   +1 more source

Multimodal Cross‐Attentive Graph‐Based Framework for Predicting In Vivo Endocrine Disruptors

Advanced Science, EarlyView.
A multimodal cross‐attentive graph neural network integrates molecular graphs with androgen and estrogen adverse outcome pathway (AOP)–anchored in vitro assay signals to predict in vivo endocrine disruption. By fusing information on Tier‐1 AOP logits with chemical structures, the framework achieves high accuracy and provides assay‐traceable ...
Eder Soares de Almeida Santos, Gustavo Felizardo Santos Sandes, Artur Christian Garcia da Silva, Holli‐Joi Martin, Eugene N. Muratov, Rodolpho de Campos Braga, Bruno Junior Neves   +6 more
wiley   +1 more source

Learnable Diffusion Framework for Mouse V1 Neural Decoding

Advanced Science, EarlyView.
We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng, Peter S. Schwendeman, Yuanfang Guan   +2 more
wiley   +1 more source

NVIDIA Nemotron Parse 1.1

We introduce Nemotron-Parse-1.1, a lightweight document parsing and OCR model that advances the capabilities of its predecessor, Nemoretriever-Parse-1.0. Nemotron-Parse-1.1 delivers improved capabilities across general OCR, markdown formatting, structured table parsing, and text extraction from pictures, charts, and diagrams.
Chumachenko, Kateryna, Deshmukh, Amala Sanjay, Seppanen, Jarno, Karmanov, Ilia, Chen, Chia-Chih, Voegtle, Lukas, Fischer, Philipp, Wawrzos, Marek, Motiian, Saeid, Ageev, Roman, Wu, Kedi, Milesi, Alexandre, Moosaei, Maryam, Pawelec, Krzysztof, Subramanian, Padmavathy, Samadi, Mehrzad, Yu, Xin, Dear, Celina, Stoddard, Sarah, Diamond, Jenna, Oliver, Jesse, Chraghchian, Leanna, Skelly, Patrick, Balough, Tom, Xu, Yao, Scowcroft, Jane Polak, Korzekwa, Daniel, Hanley, Darragh, Bhaskar, Sandip, Roman, Timo, Sapra, Karan, Tao, Andrew, Catanzaro, Bryan   +32 more
openaire   +2 more sources

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

Advanced Science, EarlyView.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi, Di Tang, Johan Malmström, Yasaman Karami, Hamed Khakzad   +4 more
wiley   +1 more source