Results 231 to 240 of about 196,532 (314)

PEPITEM Regulates the Synovial Microenvironment During Immune‐Mediated Inflammatory Arthritis to Limit Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Here we investigate the status of the adiponectin–PEPITEM pathway in early, treatment naive rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and the therapeutic efficacy of PEPITEM administration in preclinical models. Methods Peripheral blood was isolated from patients with clinical suspect arthralgia and suspected inflammatory ...
Mussarat Wahid   +34 more
wiley   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel   +12 more
wiley   +1 more source

Posterior Arthroscopic Talar Body Nonunion Repair With Subtalar Arthrodesis

open access: yesArthroscopy Techniques, EarlyView.
Abstract Talus fractures are a rare and challenging problem for the orthopaedic surgeon. They often present following high‐speed injury mechanisms in patients with polytraumatic injuries. Diagnosis and treatment of these fractures may be delayed, at times leading to talus nonunion or malunion.
Kyle S. Ardavanis   +3 more
wiley   +1 more source

Arthroscopy‐Assisted Type 2 Posterior Horn Lateral Meniscus Transtibial Root Repair And Concurrent Inside‐Out Lateral Meniscus Horizontal Cleavage Tear Repair With an Anterolateral Ligament Reconstruction Utilizing Iliotibial Band Autograft

open access: yesArthroscopy Techniques, EarlyView.
Abstract The anterior cruciate ligament (ACL) and anterolateral ligament (ALL) play key roles in maintaining rotational stability of the knee joint. Injuries that cause ACL tears have been shown to also frequently compromise the integrity of the ALL.
Taidhgin J. Keel   +6 more
wiley   +1 more source

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen   +13 more
wiley   +1 more source

Vermilionectomy for Actinic Cheilitis Treatment-Report of 03 Cases and Brief Literature Review. [PDF]

open access: yesCase Rep Dent
Rodrigues BTG   +9 more
europepmc   +1 more source

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