Results 161 to 170 of about 9,643,739 (297)

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

open access: yesAdvanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang   +12 more
wiley   +1 more source

Depolymerization of Nylon‑6 over a Supported Ruthenium Catalyst to ε‑Caprolactam. [PDF]

open access: yesACS Environ Au
Dhakal P   +5 more
europepmc   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu   +13 more
wiley   +1 more source

Parametric Life Cycle Assessment of Chemical Recycling of Nylon-6 to Caprolactam. [PDF]

open access: yesEnviron Sci Technol
Minor AJ   +5 more
europepmc   +1 more source

Nylon 6/Polyaniline 복합체의 특성

open access: yes, 2017
학위논문(석사)--아주대학교 공학대학원 :화학생명공학과,2017. 2Engineering plastics에 도전성을 부여하는 방법은 금속 filler 또는 carbon 등 을 첨가하는 방법이 주로 이용되고 있다. 금속 filler를 첨가하는 방법은 제품의 비중의 증가, 가격의 상승, 연속 생산이 어려운 단점이 있으며, carbon을 첨가하는 방법은 낮은 도전성을 나타내는 단점을 가지고 있다. 이에 전도성 고분자를 engineering plastics과
김병수
core  

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun   +16 more
wiley   +1 more source

Studies on Nylon 6-Nylon 66 Blends

open access: yesKobunshi Kagaku, 1970
Hiroshi Mitomo, Hiroaki Tonami
openaire   +3 more sources

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