Results 241 to 250 of about 11,881 (273)

The role of regularity and synchrony of cerebellar Purkinje cells for pathological nystagmus

Annals of the New York Academy of Sciences, 2011
Previous theories assumed that the beneficial effect of the potassium channel blocker 4‐aminopyridine (4‐AP) for patients suffering from downbeat nystagmus (DBN) or episodic ataxia type 2 (EA2) is due to an increase of excitability of cerebellar Purkinje cells (PC).
Christian Rössert, Stefan Glasauer, Michael Strupp   +2 more
openaire   +3 more sources

Eye tracker based method for quantitative analysis of pathological nystagmus

2011 24th International Symposium on Computer-Based Medical Systems (CBMS), 2011
In this paper we propose a method for quantitative assessment of pathological nystagmus by using eye gaze data recorded with an eye tracker (Tobii T60). In detail, we use data acquired while patients perform two tests, the smooth pursuit and the saccadic movement test (implemented on the Tobii T60 using its API), that may indicate altered ophthalmic ...
GIORDANO, Daniela, Pino C, SPAMPINATO, CONCETTO, Di Pietro M, Reibaldi A.   +4 more
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Clinical implications of head‐shaking nystagmus in central and peripheral vestibular disorders: is perverted head‐shaking nystagmus specific for central vestibular pathology?

European Journal of Neurology, 2020
AbstractBackground and purposeThe patterns of head‐shaking nystagmus (HSN) aid in differentiation between central and peripheral vestibular disorders, and perverted HSN (pHSN) has been considered a central sign. The aim was to determine the characteristics of HSN in a large number of patients with either peripheral or central vestibular disorders in a ...
Sun-Young Oh, Juhyung Lee, Jin-Ju Kang, Tae-Ho Yang, Marianne Dieterich, Ji Soo Kim, Ji Soo Kim   +6 more
openaire   +2 more sources

Familial Positional Downbeat Nystagmus and Cerebellar Ataxia: Clinical and Pathologic Findings

Annals of the New York Academy of Sciences, 2005
Abstract: A family with progressive cerebellar ataxia is reported. The earlier signs of cerebellar dysfunction was positional downbeat nystagmus (PDBN). An autopsy of one member with PDBN, who died early in the disease of unrelated causes, showed loss of Purkinje cells primarily in the nodulus.
Jorge C. Kattah, Meena Gujrati
openaire   +3 more sources

Structural and functional MRIs disclose cerebellar pathologies in idiopathic downbeat nystagmus

Neurology, 2007
Neurologic disorders in which the etiology and pathogenesis are not yet understood are termed idiopathic. Downbeat nystagmus (DBN) is a frequent eye movement disorder that clinically manifests with oscillopsia and postural instability. Forty percent of patients with DBN are classified as having idiopathic DBN, because no underlying pathology can be ...
Katharina Hüfner, Angela Deutschländer, G. Schulte-Altedorneburg, M. Strupp, T. Stephan, Markus Holtmannspötter, Stefan Glasauer, T. Brandt, Roger Kalla, Judith Wagner   +9 more
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Failure of fixation suppression [PDF]

Neurology, 1974
Failure of visual fixation to suppress caloric nystagmus was studied quantitatively. An ocular-fixation index was defined as a measurement for determining the presence of failure of fixation suppression. The ocular-fixation index of slow-phase velocity best separated normal from abnormal caloric responses.
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Persistent geotropic nystagmus—a different kind of cupular pathology and its localizing signs

Acta Oto-Laryngologica, 2006
A persistent geotropic positional nystagmus indicates a dysfunction in the lateral semicircular canal with a cupula of less specific weight than the surrounding endolymph. It is possible to determine the side of the affected cupula by recording the nystagmus pattern in yaw and pitch plane.To identify the clinical features in patients with a persistent ...
Johan Bergenius, Tatjana Tomanovic
openaire   +3 more sources

Downbeat nystagmus and pathology at cervicomedullary junction [PDF]

Neurology, 1981
Ralph J. Pagano, José Biller
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[Pathologic nystagmus and related phenomena. A review].

Der Nervenarzt, 1985
Pathological nystagmus may be spontaneous, positional, or gaze-evoked. Peripheral vestibular nystagmus is usually rotatory, the horizontal component being most prominent. It is - in contrast to a central vestibular nystagmus - strongly inhibited by fixation.
S, Biedert, R, Reuther
openaire   +1 more source

On Pathological Spontaneous and Positional Nystagmus

ORL, 1963
W.J. Oosterveld, S. Zelig, A.J. Philipszoon, J. Vozza, J.H. Bos   +4 more
openaire   +3 more sources