O32 Ontogeny of human kidney OCT2 expression across the paediatric age range [PDF]
BackgroundIn adults, the organic cation transporter 2 (protein name OCT2, gene name SLC22A2) is localised in the kidney proximal tubules where it mediates organic cation secretion. Hence, the transporter plays a role in the disposition and excretion of several drugs and drug-drug interactions.
Nori J.L. Smeets+6 more
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O32 TREATMENT OF FASCIAL DEHISCENCE IS IMPROVED BY MESH REINFORCEMENT [PDF]
Abstract Aim In 2014 fascial dehiscence (FD) was treated with re-suturing the fascia as the only measure in half of the cases at our institution, with discouraging re-rupture and incisional hernia (IH) rates.
Patrik Kjärsgård Pettersson+1 more
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O32 Defining normal ranges for 96-hour wireless PH monitoring using healthy controls [PDF]
Introduction Technology now allows up to 96-hour wireless pH-recording in clinical practice; however, no normal values exist for this methodology. This study acquired 96-hour esophageal pH recordings in healthy controls (HC) and compared these values against measurements in patients with endoscopic evidence of gastroesophageal reflux disease (GORD ...
Mark A. Fox+6 more
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O32: TRANSPARENCY IN SURGICAL RANDOMISED CONTROLLED TRIALS: CROSS-SECTIONAL, OBSERVATIONAL STUDY [PDF]
Abstract Introduction Randomised controlled trials (RCT) often provide the scientific basis on which commissioning and treatment decisions are made. It is essential that their results and methods are reported transparently.
Ewen M Harrison+7 more
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O32 Use of In-Situ simulation to tackle latent threats in a major haemorrhage protocol – difficulties and determination [PDF]
Introduction Major Haemorrhage carries a high mortality of 32%1 and requires a co-ordinated response from bloodbank, clinical areas and porters. In-situ simulation can reveal latent threats which are not shown by Patient Safety Incident reporting.2 Repeated simulations allow iterative Quality Improvement (QI) to mitigate latent threats.
Margarita Burmester+5 more
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O32 Skin proteome investigation in cutaneous lupus erythematosus (CLE) reveals novel unique disease pathways [PDF]
Background Cutaneous Lupus Erythematosus (CLE) is an autoimmune disease. It can be limited to the skin or be one of manifestations of systemic LE (SLE). The typical histopathologic pattern in CLE/SLE is interface dermatitis, which can also be observed in dermatomyositis (DM).
Marie Wahren-Herlenius+10 more
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O32 Digital artery volume index (DAVIX©) predicts the onset of future digital ulcers in patients with SSc [PDF]
Abstract Background Digital Ulcer Disease is a main vascular manifestation of Systemic Sclerosis (SSc) caused by progressive narrowing of digital arteries with consequent tissue ischemia. Time of flight angiography (TOF) is an MRI technique based on flow-related enhancement of spins entering into an ...
Klodian Gjeloshi+11 more
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O32 Evolving ethnographic sensibilities: using actor-network theory in health services research [PDF]
Background In a recent editorial,1 discuss the use of ethnography and the ‘ethnographic label’ in health services research. Commenting on Vindrola-Padros & Vindrola-Padros’2 review of ‘rapid ethnographies’, the authors encourage further debate around the use of the ethnographic label in this scholarly field.
Sara Donetto, Amit Desai
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Self-aggregation of zinc bacteriochlorophyll-d analogs with an acylhydrazone moiety as the 13-keto-carbonyl alternative. [PDF]
Zinc bacteriochlorophyll‐d analogs possessing an acylhydrazone moiety as the 13‐keto‐carbonyl alternative were prepared. Similar to self‐aggregation in chlorosomes, synthetic models with R=(CH2)1~6H self‐aggregated in an aqueous Triton X‐100 solution to give red‐shifted and broadened visible absorption bands with intense CD bands.
Fujii S, Tamiaki H.
europepmc +2 more sources
A comparison of microcrystal electron diffraction and X-ray powder diffraction for the structural analysis of metal-organic frameworks. [PDF]
Microcrystal electron diffraction (microED) was used to determine the crystal structure of a recently synthesized metal–organic framework (MOF) from powder crystallites. The structural descriptions of two other MOFs by microED are compared with results previously published using X‐ray powder diffraction supported by density functional theory ...
Biehler E+5 more
europepmc +2 more sources