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Structures of the O-antigens of Escherichia coli O13, O129, and O135 related to the O-antigens of Shigella flexneri

Carbohydrate Research, 2010
O-Polysaccharides (O-antigens) were isolated from Escherichia coli O13, O129, and O135 and studied by chemical analyses along with 2D (1)H and (13)C NMR spectroscopy. They were found to possess a common -->2)-l-Rha-(alpha1-->2)-l-Rha-(alpha1-->3)-l-Rha-(alpha1-->3)-d-GlcNAc-(beta1--> backbone, which is a characteristic structural motif of the O ...
Andrei V. Perepelov   +7 more
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Structure of the O-antigen of Yersinia pseudotuberculosis O:4a revised

Carbohydrate Research, 2009
The O-specific polysaccharide was isolated by mild acid degradation of the lipopolysaccharide of Yersinia pseudotuberculosis O:4a and studied by NMR spectroscopy, including 2D ROESY and (1)H, (13)C HMBC experiments. The following structure of the pentasaccharide repeating unit of the polysaccharide was established, which differs from the structure ...
Rima Z. Shaikhutdinova   +7 more
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Detection of O antigens inEscherichia coli

Animal Health Research Reviews, 2011
AbstractLipopolysaccharide on the surface ofEscherichia coliconstitutes the O antigens which are important virulence factors that are targets of both the innate and adaptive immune systems and play a major role in host–pathogen interactions. O antigens are responsible for antigenic specificity of the strain and determine the O serogroup.
Chitrita DebRoy   +2 more
openaire   +3 more sources

Genetics, Biosynthesis and Assembly of O-Antigen

2011
Lipopolysaccharide (LPS), a major component of the outer leaflet of the Gram-negative bacterial outer membrane [1], consists of lipid A, core oligosaccharide (OS), and O-specific polysaccharide or O-antigen [1,2]. LPS is a surface molecule unique to Gram-negative bacteria that plays a key role as an elicitor of innate immune responses, ranging from ...
Valvano, Miguel   +2 more
openaire   +2 more sources

O antigen-dependent mutant of bacteriophage T5

Journal of Virology, 1984
A T5 mutant is described which showed normal infection of Escherichia coli F but virtually no infection of cells lacking the E. coli F O antigen. This was due to very poor adsorption to the O antigen-deficient cells. Inactivation kinetics with anti-T5 serum and adsorption and desorption kinetics to receptor-deficient E.
D Bryniok, K J Heller
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Regulation of O-Antigen Biosynthesis in Yersinia enterocolitica

2006
Lipopolysaccharide (LPS) is a glycolipid present in the outer membrane (OM) of Gram-negative bacteria. The LPS molecule consists of three regions: (i) the lipid A, a polar glycolipid in which a disaccharide backbone is replaced with six or seven fatty acid; (ii) the core, an oligosaccharide often rich in negatively charged groups and, (iii) the O ...
openaire   +4 more sources

Role of O-antigen variation in the immune response

Trends in Microbiology, 1995
The O antigen is an extremely variable surface polysaccharide of Gram-negative bacteria. This variation is thought to allow the various clones of a species each to present a surface that offers a selective advantage in the niche occupied by that clone.
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Comparative Study of Typhoid O Antigens

American Journal of Clinical Pathology, 1965
Dickinson C   +3 more
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