Results 1 to 10 of about 2,777 (73)

Comparative Efficacy and Safety of Anakinra and Canakinumab in Patients With VEXAS Syndrome: An International Multicenter Study. [PDF]

open access: yesArthritis Rheumatol
Objective The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) syndrome. Methods This multicenter international study includes patients with VEXAS from France, Israel, and Italy treated with ...
Eviatar T   +35 more
europepmc   +2 more sources

The PNH French Working Group Experience: Building a Strong Network of Cytometrists. [PDF]

open access: yesInt J Lab Hematol
ABSTRACT Introduction The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations. Methods Thirty‐five French and Belgian laboratories equipped with 2‐ or 3‐laser cytometers applied three different panels with or without FLAER reagent in 305 samples.
Wagner-Ballon O   +5 more
europepmc   +2 more sources

Intent to Treat Analysis of the Primary and Secondary Outcomes for the ODINN Intact Fish Skin Graft for Deep Diabetic Foot Wounds Trial. [PDF]

open access: yesInt Wound J
ABSTRACT There is a significant need for trials that evaluate the treatment of University of Texas (UT) grade 2 and 3 diabetic foot ulcers (bone, joint, or tendon exposed wounds). We undertook a trial looking at the effect of intact fish skin graft (IFSG) on these deep and difficult‐to‐heal ulcers.
Dardari D   +19 more
europepmc   +2 more sources

Clinical Trial Protocol for PERFECT: A Randomised Controlled Trial Comparing the Efficiency and Tolerance of Transperineal Fusion Versus Transrectal Imaging-targeted Prostate Biopsies (CCAFU-PR1 Study)

open access: yesEuropean Urology Open Science, 2022
PERFECT is a multicentre randomised controlled clinical trial that evaluates the efficiency of fusion magnetic resonance imaging–targeted biopsies in the transperineal (TP) versus transrectal (TR) approach in terms of the detection of significant cancers.
Alae Touzani   +12 more
doaj   +1 more source

Vasectomy and Risk of Prostate Cancer: A Systematic Review and Meta-analysis

open access: yesEuropean Urology Open Science, 2022
Context: Previous reports have shown an association between vasectomy and prostate cancer (PCa). However, there exist significant discrepancies between studies and systematic reviews due to a lack of strong causal association and residual confounding ...
Michael Baboudjian   +16 more
doaj   +1 more source

In-Person and Remote Workshops for People With Neurocognitive Disorders: Recommendations From a Delphi Panel

open access: yesFrontiers in Aging Neuroscience, 2022
Workshops using arts and board games are forms of non-pharmacological intervention widely employed in seniors with neurocognitive disorders. However, clear guidelines on how to conduct these workshops are missing.
Valeria Manera   +32 more
doaj   +1 more source

Association between annual twin delivery volume and severe postpartum hemorrhage in twin pregnancies

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess the association between the risk of severe postpartum hemorrhage (PPH) and the annual twin delivery volume of maternity units. Methods JUmeaux MODe d'Accouchement (JUMODA) was a national observational prospective population‐based cohort of twin deliveries in 176 French maternity units performing more than 1500 annual ...
Victoire Pauphilet   +6 more
wiley   +1 more source

Post-transplant cyclophosphamide versus anti-thymocyte globulin after reduced intensity peripheral blood allogeneic cell transplantation in recipients of matched sibling or 10/10 HLA matched unrelated donors: final analysis of a randomized, open-label, multicenter, phase 2 trial

open access: yesBlood Cancer Journal
The use of post-transplantation cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis is not established after reduced intensity conditioning (RIC) hematopoietic stem cell transplantation (HSCT) from fully matched donors.
Eolia Brissot   +18 more
doaj   +1 more source

Snapshots of Motion: A Novel Structural Intermediate Reveals Conserved Dynamics in Archaeal DNA Ligases

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas   +3 more
wiley   +1 more source

Surgical Management of Zollinger‐Ellison Syndrome in Multiple Endocrine Neoplasia Type 1 an AFCE and GTE Cohort Study. (Association Francophone de Chirurgie Endocrinienne and Groupe d'étude des Tumeurs Endocrines)

open access: yesWorld Journal of Surgery, EarlyView.
To describe surgical indications, procedures and outcomes in patients operated for Zollinger‐Ellison syndrome (ZES) in multiple endocrine neoplasia type 1 (MEN1) using a large nationwide cohort. ABSTRACT Objective To describe surgical indications, procedures and outcomes in patients operated for Zollinger‐Ellison syndrome (ZES) in multiple endocrine ...
Sébastien Gaujoux   +27 more
wiley   +1 more source

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