Results 1 to 10 of about 54,621 (145)

Clinical Trial Protocol for PERFECT: A Randomised Controlled Trial Comparing the Efficiency and Tolerance of Transperineal Fusion Versus Transrectal Imaging-targeted Prostate Biopsies (CCAFU-PR1 Study)

open access: yesEuropean Urology Open Science, 2022
PERFECT is a multicentre randomised controlled clinical trial that evaluates the efficiency of fusion magnetic resonance imaging–targeted biopsies in the transperineal (TP) versus transrectal (TR) approach in terms of the detection of significant cancers.
Alae Touzani   +12 more
doaj   +1 more source

Vasectomy and Risk of Prostate Cancer: A Systematic Review and Meta-analysis

open access: yesEuropean Urology Open Science, 2022
Context: Previous reports have shown an association between vasectomy and prostate cancer (PCa). However, there exist significant discrepancies between studies and systematic reviews due to a lack of strong causal association and residual confounding ...
Michael Baboudjian   +16 more
doaj   +1 more source

In-Person and Remote Workshops for People With Neurocognitive Disorders: Recommendations From a Delphi Panel

open access: yesFrontiers in Aging Neuroscience, 2022
Workshops using arts and board games are forms of non-pharmacological intervention widely employed in seniors with neurocognitive disorders. However, clear guidelines on how to conduct these workshops are missing.
Valeria Manera   +32 more
doaj   +1 more source

Deep brain stimulation of the thalamus for intractable epilepsy (FRANCE study): A randomized clinical trial

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the efficacy and safety of deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) compared with best medical treatment (BMT) in patients with drug‐resistant epilepsy (DRE).
Stéphan Chabardès   +30 more
wiley   +1 more source

Post-transplant cyclophosphamide versus anti-thymocyte globulin after reduced intensity peripheral blood allogeneic cell transplantation in recipients of matched sibling or 10/10 HLA matched unrelated donors: final analysis of a randomized, open-label, multicenter, phase 2 trial

open access: yesBlood Cancer Journal
The use of post-transplantation cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis is not established after reduced intensity conditioning (RIC) hematopoietic stem cell transplantation (HSCT) from fully matched donors.
Eolia Brissot   +18 more
doaj   +1 more source

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange   +16 more
wiley   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto   +21 more
wiley   +1 more source

Association between annual twin delivery volume and severe postpartum hemorrhage in twin pregnancies

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess the association between the risk of severe postpartum hemorrhage (PPH) and the annual twin delivery volume of maternity units. Methods JUmeaux MODe d'Accouchement (JUMODA) was a national observational prospective population‐based cohort of twin deliveries in 176 French maternity units performing more than 1500 annual ...
Victoire Pauphilet   +6 more
wiley   +1 more source

Hematopoietic stem cell transplantation for DLBCL: a report from the European Society for Blood and Marrow Transplantation on more than 40,000 patients over 32 years

open access: yesBlood Cancer Journal
Autologous(auto-) and allogeneic(allo-) hematopoietic stem cell transplantation (HSCT) are key treatments for relapsed/refractory diffuse large B-cell lymphoma (DLBCL), although their roles are challenged by CAR-T-cells and other immunotherapies.
Philipp Berning   +30 more
doaj   +1 more source

Transcriptomic comparative study between canalicular adenoma and HMGA2::WIF1 canalicular‐like pleomorphic adenoma

open access: yesThe Journal of Pathology, EarlyView.
Abstract Canalicular adenoma (CA) is a benign salivary gland tumor predominantly affecting the upper lip and is characterized by monomorphic epithelial cells arranged in branching cords within a loose and vascularized stroma. Unlike pleomorphic adenoma (PA), CA lacks a chondroid matrix and exhibits specific histological features, such as high cuboidal ...
Ziyad Alsugair   +8 more
wiley   +1 more source

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