Results 191 to 200 of about 1,922,582 (355)
Global nutrition transition and the pandemic of obesity in developing countries.
B. Popkin, L. Adair, S. Ng
semanticscholar +1 more source
RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin
Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain+9 more
wiley +1 more source
Reimagining obesity analyses: the need for new approaches to study obesity-related multimorbidity and event cascades. [PDF]
Yao Z, Dardari ZA, Blaha MJ.
europepmc +1 more source
Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen+17 more
wiley +1 more source
Addressing the challenge of obesity in primary care: a review of effective interventions and implementation strategies. [PDF]
Khani M+7 more
europepmc +1 more source
Trends in Obesity Among Adults in the United States, 2005 to 2014.
K. Flegal+4 more
semanticscholar +1 more source
Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim+9 more
wiley +1 more source