Results 61 to 70 of about 3,115,358 (389)

Association of the leptin receptor Q223R (rs1137101) polymorphism with obesity measures in Sri Lankans [PDF]

, 2020
OBJECTIVE: The role of genetic factors in the development of obesity is largely unreported in Sri Lankans. The Q223R (rs1137101) single nucleotide polymorphism (SNP) of the leptin receptor (LEPR) gene has been associated with obesity measures in various ...
Dalton, C.F., Fernando, D.J., Illangasekera, Y.A., Kumarasiri, P.V.R.   +3 more
core   +1 more source

Non-Alcoholic Fatty Liver Disease in Lean and Non-Obese Individuals: Current and Future Challenges [PDF]

, 2021
Mohammad Shafi Kuchay, José Ignacio Martínez‐Montoro, Narendra S. Choudhary, José Carlos Fernández‐García, Bruno Ramos‐Molina   +4 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Childhood obesity and educational attainment : A systematic review [PDF]

, 2011
Background This report describes the findings and methods of a systematic review of research which explores the relationship between obesity and educational attainment.
Caird, Jenny, Kavanagh, Josephine, O'Mara, Alison, Oliver, Kathryn, Oliver, Sandy, Stansfield, Claire, Thomas, James   +6 more
core   +1 more source

The Effect of Short-Term Consumption of Lactic Acid Bacteria on the Gut Microbiota in Obese People [PDF]

, 2022
Inna Burakova, Yuliya Smirnova, Mariya Gryaznova, Mikhail Syromyatnikov, Pavel A. Chizhkov, Е. С. Попов, В. Н. Попов   +6 more
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Childhood Obesity and Familial Hypercholesterolemia: Genetic Diseases that Contribute to Cardiovascular Disease [PDF]

, 2014
Childhood obesity occurs as the result of an imbalance between caloric intake and energy expenditure. Genetic risk factors for obesity have become an area of research due to its permanency.
Caudle, Alyssa
core   +1 more source

Double burden of malnutrition among urban Bengalee adolescent boys in Midnapore, West Bengal, India [PDF]

, 2012
Malnutrition is an important public health problem worldwide. Therefore a study was undertaken to assess the prevalence of adolescent thinness, overweight and obesity in Midnapore town, West Bengal, India.
D Mahalanabis, K Bose, R Khongsdier, S Bisai, S Bisai   +4 more
core   +3 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Defining an epidemic:The body mass index in British and American obesity research 1960-2000 [PDF]

, 2014
Between the 1970s and the mid‐1990s the body mass index (BMI) became the standard means of assessing obesity both in populations and in individuals, replacing previously diverse and contested definitions of excess body weight.
Amsterdamska, Aronowitz, Aronowitz, Bacon, Baird, Baird, Berridge, Berridge, Berridge, Berridge, Bowker, Bray, Bray, Bray, British Nutrition Foundation (BNF), Busch, Campos, Craddock, Crawford, Department of Health (DoH), Department of Health and Social Security/Medical Research Council (DHSS/MRC), Desrosieres, Epstein, Fletcher, Fye, Gaesser, Gard, Garrow, Garrow, Garrow, Garrow, Government Office for Science, Hacking, Hacking, Hautvast, Hilgartner, James, James, Jasanoff, Jasanoff, Keys, Kromhout, Kuczmarski, Kuczmarski, Kuhn, Monaghan, National Institutes of Health Panel on Obesity, O'Connell, Oddy, Office of Health Economics, Oliver, Oppenheimer, Oppenheimer, Pickersgill, Pickersgill, Pringle, Rothstein, Royal College of Physicians, Scottish Intercollegiate Guidelines Network (SIGN), Sims, Smith, Timmermann, Timmermans, Timmermans, Timmermans, Tunstall-Pedoe, VanItalllie, West, WHO, WHO, World Health Organization (WHO)   +70 more
core   +1 more source