Results 71 to 80 of about 825,693 (259)
Frontiers in PediatricsObjectivesChildhood obesity is a growing health problem and requires a tailored treatment. This study explored the sex differences in cardiovascular risk factors in children/adolescents with obesity and in response to a weight loss intervention ...
Luisa Gilardini +5 more
doaj +1 more source
Differentially methylated loci in NAFLD cirrhosis are associated with key signaling pathways
Clinical Epigenetics, 2018 Altered DNA methylation events contribute to the pathogenesis and progression of metabolic disorders, including nonalcoholic fatty liver disease (NAFLD).
Glenn S. Gerhard +6 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A hybrid‐nested microneedle/cryogel scaffold (MQW‐CMg‐MOF) is designed for efficient biofilm removal and accelerated healing of diabetic wounds. The scaffold shows substantial biofilm removal in vitro and in a preclinical diabetic swine biofilm‐infected wound model compared to the control.
Syed Muntazir Andrabi +11 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
wiley +1 more source
Advanced Materials Interfaces, EarlyView.Nano‐octahedron Co3O4 decorated graphene composite electrode for selective and simultaneous detection of dopamine. The detection limit of 0.09 µM, and linear range from 1 to 500 µM are reported. The synergistic effect of nano octahedron Co3O4 and graphene results in excellent performance of the sensor in terms of selectivity and sensitivity.
Swathi Tharani Dharmalingam +5 more
wiley +1 more source
Mitochondrial Regulation of the Muscle Microenvironment in Critical Limb Ischemia
Frontiers in Physiology, 2015 Critical limb ischemia (CLI) is the most severe clinical presentation of peripheral arterial disease and manifests as chronic limb pain at rest and/or tissue necrosis.
Terence E. Ryan +11 more
doaj +1 more source
Advanced Materials Technologies, EarlyView.Non‐faradaic label‐free impedimetric determination of cortisol is demonstrated with gold nanoparticles (AuNP) functionalized laser‐induced graphene interdigitated electrodes (LIG‐IDE). The AuNP functionalized LIG‐IDE exhibits remarkable characteristics including good logarithmic linear range, high reproducibility, repeatability, and robust selectivity.
Kyle Duke +9 more
wiley +1 more source
Artificial Intelligence and Data Mining in Health Research (AI/MDRS)
McGill Journal of Medicine, 2022 The Cardiometabolic Health and Obesity Research Network (rrCMDO)
doaj +1 more source
A Dynamic Double‐Flow Gut‐On‐Chip Model for Predictive Absorption Studies In Vitro
Advanced Materials Technologies, EarlyView.This study presents a novel millifluidic gut‐on‐chip model using the MIVO® device to replicate human intestinal conditions. Dynamic co‐culture of CaCo‐2 and HT‐29 cells accelerates differentiation, modulates mucus thickness, and enhances barrier function.
Maria Elisabetta Federica Palamà +6 more
wiley +1 more source