Results 191 to 200 of about 454,476 (312)

Completion vs. early discontinuation of chemotherapy and the impact on 5‐year all‐cause mortality in women treated for early‐stage breast cancer from 2015 to 2020: A cohort study using a target trial emulation approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Chemotherapy is given for early‐stage breast cancer; however, some patients discontinue before completing all planned cycles. This study investigated the impact of early chemotherapy discontinuation on treatment outcomes. Methods This retrospective cohort study used a target trial emulation framework to conduct a causal analysis of the all‐
Luke Steventon, Chengsheng Ju, Kenneth K. C. Man, Rebecca Roylance, Diego Ottaviani, Chiara Creed, Michal Sladkowski, Alec Wisner, Li Wei, Pinkie Chambers   +9 more
wiley   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

The Impact of Prior Obesity Surgery on Bleeding after Abdominal Body Contouring Surgery. [PDF]

Plast Reconstr Surg Glob Open
Badran S, Braizat O, Aljassem G, Alyazji Z, Farsakoury R, Iskeirjeh S, Asim M, Glass GE, Muneer M.   +8 more
europepmc   +1 more source

Endoscopic sleeve gastroplasty is feasible after failed modified primary obesity surgery endoluminal procedure. [PDF]

VideoGIE, 2021
Bove V, Pontecorvi V, Valeria Matteo M, Costamagna G, Boškoski I.   +4 more
europepmc   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

The impact of obesity surgery on newborn anthropometrics in women with and without polycystic ovary syndrome. [PDF]

Arch Gynecol Obstet
Huke CJ, Romsaas T, Vanky E, Huse K, Ødegård R, Nymo S, Hoff DAL, Sandvik J.   +7 more
europepmc   +1 more source

Obesity Surgery and Cancer: What Are the Unanswered Questions? [PDF]

Front Endocrinol (Lausanne), 2020
Castagneto-Gissey L, Casella-Mariolo J, Casella G, Mingrone G.   +3 more
europepmc   +1 more source

Generalized Anxiety as a Risk Factor for Dysfunctional Eating Behavior after Obesity Surgery during the COVID-19 Pandemic. [PDF]

Int J Environ Res Public Health, 2021
Pfeiffer C, Schweda A, Schüren LC, Niedergethmann M, Steinbach J, Rentrop V, Robitzsch A, Dörrie N, Bäuerle A, Teufel M, Skoda EM, Weismüller B.   +11 more
europepmc   +1 more source

Asia's Growing Contribution to Obesity Surgery Research: A 40-year Bibliometric Analysis. [PDF]

Obes Surg
Liu Z, Wang H, Fan D, Xu T, Wan F, Xia Q.   +5 more
europepmc   +1 more source

Humans are not unique: difficult birth is common in placental mammals

Biological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source