Results 91 to 100 of about 5,434,710 (294)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Objeto de contradicción Aproximaciones al ready-made en la obra temprana de Robert Venturi, 1959-1968

Cuaderno de Notas, 2019
Resumen Este texto pretende analizar un aspecto concreto de la idea de “convención” en la obra de Robert Venturi: la incorporación del objeto cotidiano a la arquitectura en un contexto, el del Pop, en el que parece recuperarse, transformada, la ...
Enrique Encabo Seguí, Inmaculada Esteban Maluenda   +1 more
doaj   +1 more source

SIMCO: SIMilarity-based object COunting

, 2019
We present SIMCO, the first agnostic multi-class object counting approach. SIMCO starts by detecting foreground objects through a novel Mask RCNN-based architecture trained beforehand (just once) on a brand-new synthetic 2D shape dataset, InShape; the ...
Cristani, Marco, Giachetti, Andrea, Godi, Marco, Joppi, Christian   +3 more
core  

UA-DETRAC: A New Benchmark and Protocol for Multi-Object Detection and Tracking

, 2020
In recent years, numerous effective multi-object tracking (MOT) methods are developed because of the wide range of applications. Existing performance evaluations of MOT methods usually separate the object tracking step from the object detection step by ...
Cai, Zhaowei, Chang, Ming-Ching, Du, Dawei, Lei, Zhen, Lim, Jongwoo, Lyu, Siwei, Qi, Honggang, Wen, Longyin, Yang, Ming-Hsuan   +8 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Legislative relations as a form of law application

RUDN Journal of Law
The field of public relations within the realm of legislative processes of the state undergoes theoretical and legal analysis. These social relations, which arise from the implementation of legislative activities by legislative entities, are proposed to ...
Vasily V. Trofimov
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source