Results 111 to 120 of about 5,416,136 (295)

Взаємозв'язок сутності і знання: від витоків пізньої схоластики до сучасності / Interrelation of Essense and Knowledge: from Times of the Late Scholasticism to Modern Times

Актуальні питання суспільних наук та історії медицини, 2015
Скрицька Наталія Взаємозв'язок сутності і знання: від витоків пізньої схоластики до сучасності У статті аналізується поняття сутності як основа філософського пізнання навколишньої дійсності з часів середньовічного мислення до сьогодення. Прослідковується
Скрицька Наталія
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Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Developing standards for surveying, measuring, and mapping underground objects using the GPR method for Vietnam

Geodesy and Cartography
In the context of rapid urbanization, detailed investigation of underground objects in the shallow layer is very important for safe and efficient urban planning, construction, and operation.
Phi Son Nguyen, Thanh Thuy Nguyen, Ngoc Long Dao, Chi Thinh Le, Thi Hue Nguyen   +4 more
doaj   +1 more source

OMG/CORBA: An object-oriented middleware [PDF]

, 2001
ANSA (Advanced Network Systems Architecture), Baker, Emmerich, Monson-Haefel, Mowbray, Mowbray, Object Management Group (OMG), Object Management Group (OMG), Open Group, Orfali, Orfali, Otte, Siegel, Slama, Vogel, X/Open Group   +15 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

JURIDICAL CHARACTERISTICS OF PREVARICATION STEALAGE UNDER THE MODERN RUSSIAN CRIMINAL CODE

Russian Journal of Economics and Law, 2008
The article investigates the issue of juridical evaluation of prevarication stealage and shows the specific features of the object of encroachment.
A. G. Bezverkhov
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