Results 121 to 130 of about 1,274,807 (250)

Validation of a force transducer-embedded platform as an alternative to handles in weight perception research. [PDF]

Behav Res Methods
Harris JWC, Murphy MJ, Chouinard PA.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A clinically validated AI framework for kidney cancer detection and characterization. [PDF]

Commun Med (Lond)
Petryshak B, Iljin M, Denissova A, Ariva J, Häide T, Lasn V, Reim M, Ivaniv I, Lillsaar T, Vilt H, Leht A, Karask A, Kiudma G, Käpp R, Salumaa P, Ilves P, Fishman D.   +16 more
europepmc   +1 more source

Object marking in Swahili is topic agreement

Jezikoslovlje, 2018
In diesem Aufsatz diskutiere ich die Objektmarkierung am Verb im Swahili, einer Bantu-Sprache. Nachdem ich die Kontexte präsentiert habe, in denen die Markierung am Verb optional bzw. Obligatorisch ist, zeige ich dass der informationsstrukturelle Status des Objekts die Präsenz der Objektmarkierung am Verb determiniert. Wenn das Objekt gegeben ist, dann
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Active Inference Modeling of Socially Shared Cognition in Virtual Reality. [PDF]

Sensors (Basel)
Arima Y, Okada M.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Timed image naming evaluation for adults (TIME) using BOSS images. [PDF]

PLoS One
Heuer S, Briska C, Shah-Basak P, Pillay S.   +3 more
europepmc   +1 more source