Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Integration of 2D and 3D Imaging Descriptors with Large Language Models for Assessing Pediatric Foreign-Body Aspiration Risk. [PDF]
Gregori D +10 more
europepmc +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Improving Use of Social Communicative Gestures by Children with Autism. [PDF]
Barall RJ, Shillingsburg MA.
europepmc +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
A Deep Learning Approach for Pixel-Level Material Classification via Hyperspectral Imaging. [PDF]
Sifnaios S +5 more
europepmc +1 more source
Development and Validation of an Algorithm to Objectively Quantify Adherence to Offloading Interventions. [PDF]
Yalla SV +4 more
europepmc +1 more source
Active Inference Modeling of Socially Shared Cognition in Virtual Reality. [PDF]
Arima Y, Okada M.
europepmc +1 more source
Real-time identification and quantification of apple scab on fruit in preharvest and postharvest conditions using YOLO11: a deep learning approach. [PDF]
Leiva F, Rebeaud SG, Christen D.
europepmc +1 more source
A Clinical Quality-Assurance Panel for Patient-Facing Black-Box Large Language Models in Healthcare: Anchored Forced-Choice Drift Monitoring for Sensitive Communication. [PDF]
Harada Y.
europepmc +1 more source

