Results 231 to 240 of about 41,772 (257)

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

Research on an improved RT-DETR-based model for rice disease detection. [PDF]

PLoS One
Zhang Y, Shen C, Xiong Y.
europepmc   +1 more source

Piezoelectric Surface Charge and Dynamic Stimulation Synergize to Promote Cardiac Myoblast Alignment and Maturation

Advanced Healthcare Materials, EarlyView.
Surface polarization of PVDF films combined with mechanical stimulation generates piezoelectric electrical cues that modulate cardiomyoblast behaviour. Non‐poled and poled PVDF substrates provide distinct electroactive microenvironments influencing cell adhesion, proliferation, and differentiation.
Rafaela M Meira, Sylvie Ribeiro, Senentxu Lanceros‐Mendez, Clarisse Ribeiro   +3 more
wiley   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Septin5 deficiency impairs both recent and remote contextual fear memory. [PDF]

Mol Brain
Ageta-Ishihara N, Fukumasu N, Sakakibara K, Fujii K, Koshidaka Y, Katsuragawa S, Tanigaki K, Hiramoto T, Kang G, Hiroi N, Fukazawa Y, Miyakawa T, Takao K, Kinoshita M.   +13 more
europepmc   +1 more source

Erratic Maternal Care Induces Avoidant-Like Attachment Deficits in a Mouse Model of Early Life Adversity. [PDF]

eNeuro
MacDowell Kaswan ZA, Bowers C, Teplyakov I, Sibtain A, Munoz-Martin J, Ahmed S, Kaffman L, Giuliano L, Dietrich MO, Kaffman A.   +9 more
europepmc   +1 more source

Development and Validation of a Wearable Softness Sensor Based on Fingernail Deformation and an Inertial Measurement Unit for Quantifying Palpation. [PDF]

Cureus
Ueda S, Fukuda H.
europepmc   +1 more source

Dismantling the Diagnostic Construct of Borderline Personality Disorder: A Critical Discourse Analysis. [PDF]

Int J Ment Health Nurs
Cobbaert L, Maloney E, Harding K, James S.   +3 more
europepmc   +1 more source

From single scenes to extended scenarios: The role of the ventromedial prefrontal cortex in the construction of imagery-rich events. [PDF]

PLoS One
Taube J, Leelaarporn P, Bilzer M, Stirnberg R, Sagik Y, McCormick C.   +5 more
europepmc   +1 more source

The Relationship Between Anxiety, Stress, Depression, Traumatic Childbirth Perception, and Prenatal Attachment in Pregnant Women: A Cross-Sectional Study. [PDF]

Depress Anxiety
Yücesoy H, Yildirim F, Arar MA, Erbil N.   +3 more
europepmc   +1 more source