Results 51 to 60 of about 294,479 (334)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
Definitions and Computational Properties of OCL: A Systematic Review
IEEE AccessObject Constraint Language (OCL) plays a pivotal role in Model Driven Architecture (MDA), an important applied software engineering concept created over a quarter of a century ago. The expressiveness and precision of the primary specification language in
Goran Rajic, Vlado Sruk
doaj +1 more source
Query Migration from Object Oriented World to Semantic World
International Journal of Interactive Multimedia and Artificial Intelligence, 2016 In the last decades, object-oriented approach was able to take a large share of databases market aiming to design and implement structured and reusable software through the composition of independent elements in order to have programs with a high ...
Nassima Soussi, Mohamed Bahaj
doaj +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Verifying the structure and behavior in UML/OCL models using satisfiability solvers
IET Cyber-Physical Systems, 2016 Due to the ever increasing complexity of embedded and cyber-physical systems, corresponding design solutions relying on modelling languages such as Unified Modelling Language (UML)/Object Constraint Language (OCL) find increasing attention.
Nils Przigoda +4 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Towards a metric suite for OCL expressions expressed within UML/OCL models
Journal of Computer Science and Technology, 2004 UML models quality is clearly a crucial issue that must be evaluated at the initial stages of object-oriented software development, in order to get software products with better quality.
Luis A. Reynoso +2 more
doaj
PyFml - a Textual Language For Feature Modeling
, 2018 The Feature model is a typical approach to capture variability in a software product line design and implementation. For that, most works automate feature model using a limited graphical notation represented by propositional logic and implemented by ...
Al-Azzawi, A. F.
core +1 more source
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source