Results 61 to 70 of about 21,421 (257)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Animacy, definiteness, and world knowledge interactions in DOM in Spanish

open access: yesBorealis: An International Journal of Hispanic Linguistics
This article brings together insights from several proposals regarding differential object marking (DOM) in Spanish. It states observations about prominence, saliency, or atypicality of the object (Aissen 2003; Fábregas 2013; García García 2007 ...
Luis H. González
doaj   +1 more source

Differential place marking and differential object marking

open access: yesSTUF - Language Typology and Universals, 2019
AbstractThis paper gives an overview of differential place marking phenomena and formulates a number of universals that seem to be well supported. Differential place marking is a situation in which the coding of locative, allative or ablative roles depends on subclasses of nouns, in particular place names (toponyms), inanimate common nouns and human ...
openaire   +4 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Differential Object Marking and discourse prominence in Spanish

open access: yesIsogloss
Spanish, like many other Romance and non-Romance languages, shows Differential Object Marking (DOM), i.e., some direct objects are morphologically marked by the prepositional marker a ‘to’, while others remain unmarked.
Klaus von Heusinger   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Object Case Marking: English Influence on the Use of Estonian by Three Estonian-English Bilingual Children

open access: yesKalbotyra, 2003
The present paper reports the results of one part of a study conducted on the native language of three Estonian-English bilingual children living in Britain. This part focuses on object case marking.
Reeli Torn
doaj  

Adolescent Heritage Speakers: Morphosyntactic Divergence in Estonian Youth Language Usage in Sweden

open access: yesLanguages
Heritage language (HL) research has investigated adults and children, while adolescents have garnered far less attention, despite adolescence being a crucial time in the development of idiolects and identities, and, hence, also for language maintenance ...
Mari-Liis Korkus, Virve-Anneli Vihman
doaj   +1 more source

New structural patterns in moribund grammar: Case marking in Heritage German

open access: yesFrontiers in Psychology, 2015
Research treats divergences between monolingual and heritage grammars in terms of performance — ‘L1 attrition’, e.g. lexical retrieval — or competence — ‘incomplete acquisition’, e.g. lack of overt tense markers (e.g.
Lisa M. Yager   +6 more
doaj   +1 more source

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