Results 171 to 180 of about 2,296,333 (292)

Nocturnal intravenous gamma-hydroxybutyrate and sleep architecture in non-sedated intensive care unit patients: a polysomnographic experience. [PDF]

Crit Care
Blanchard F, Arnulf I, Clavieras N, Charbonnier-Beaupel F, Braik R, James A, Constantin JM.   +6 more
europepmc   +1 more source

Securing the Objectivity of Relative Facts in the Quantum World

Abstract This essay compares and contrasts relational quantum mechanics (RQM) with a pragmatist view of quantum theory (DP). It first explains important points of agreement. Then it points to two problems faced by RQM and sketch DP’s solutions to analogous problems. As both RQM and DP have taken the Born Rule to require relative facts,
openaire   +3 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Laddering Through Pedigrees: Family History of Malignancies in Primary Breast Cancer Patients [PDF]

A family history (FH) of breast cancer (BC) is a long recognized risk factor for developing the disease. Also, there ‍have been some reports of links between an FH and some other malignancies (mostly uterus, ovary, and prostate ‍cancers), and an ...
جعفری مجرد, الهام, حسینی اصل, سید سعید, جاویدروزی, مازیار, مهدی پور, پروین, عطری, مرتضی   +4 more
core  

Criminalizing genomic discrimination: protecting human dignity under UAE and French law. [PDF]

Front Med (Lausanne)
Gourari F, Alkrisheh MA, Ibrahim A, Akawi N, AlQodsi EM.   +4 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Care Needs and Care Options for Frail Older People Living Alone in Italy: An Exploratory Mixed Study. [PDF]

Healthcare (Basel)
Melchiorre MG, Socci M, Lamura G, Quattrini S.   +3 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Healthcare professionals' perceptions of participation and learning related to mealtimes in long-term care facilities: an interview study. [PDF]

BMC Geriatr
Allert C, Andersson S, Carlsson N, Sandgren A.   +3 more
europepmc   +1 more source