Results 71 to 80 of about 119,312 (313)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

One-Shot Scale and Angle Estimation for Fast Visual Object Tracking

IEEE Access, 2019
Visual object tracking is the process of tracking an arbitrary object in a video, where the bounding box of the object is given in the first frame. Siamese network-based visual object tracking approaches have recently received considerable attention for ...
Dong-Hyun Lee
doaj   +1 more source

Object-Aware Adaptive Convolution Kernel Attention Mechanism in Siamese Network for Visual Tracking

Applied Sciences, 2022
As a classic framework for visual object tracking, the Siamese convolutional neural network has received widespread attention from the research community.
Dongliang Yuan, Qingdang Li, Xiaohui Yang, Mingyue Zhang, Zhen Sun   +4 more
doaj   +1 more source

Intracellular objects tracking

European Journal of Cell Biology, 2007
The tracking of intracellular organelles and vesicles is becoming increasingly important for understanding cellular dynamics. Originally, the development of tracking algorithms was mainly pursued in other fields, e.g. aerospace/military/street surveillance. However, most of this algorithm is not directly applicable to live cell microscopy data. Here we
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Achieving Adaptive Visual Multi-Object Tracking with Unscented Kalman Filter

Sensors, 2022
As an essential part of intelligent monitoring, behavior recognition, automatic driving, and others, the challenge of multi-object tracking is still to ensure tracking accuracy and robustness, especially in complex occlusion environments.
Guowei Zhang, Jiyao Yin, Peng Deng, Yanlong Sun, Lin Zhou, Kuiyuan Zhang   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Measuring human-induced vibrations of civil engineering structures via vision-based motion tracking [PDF]

, 2016
We present a novel framework for measuring the body motion of multiple individuals in a group or crowd via a vision-based tracking algorithm, thus to enable studies of human-induced vibrations of civil engineering structures, such as floors and ...
Racic, V., Brownjohn, James, Shao, L, Shao, Ling, Zheng, Feng, Shao, L., Zheng, F, Brownjohn, J., Racic, Vitomir, Zheng, F.   +9 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Development of a multi-level feature fusion model for basketball player trajectory tracking

Systems and Soft Computing
To solve the problems of low matching degree, long tracking time, and low accuracy of multi-target tracking in the process of athlete motion trajectory tracking using deep learning technology, a new athlete motion trajectory tracking model was proposed ...
Tao Wang
doaj   +1 more source