Results 71 to 80 of about 75,752 (260)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Development of a Conceptual Model and Survey Instrument to Measure Conscientious Objection to Abortion Provision.

open access: yesPLoS ONE, 2016
Background and objectiveConscientious objection to abortion, clinicians' refusal to perform legal abortions because of their religious or moral beliefs, has been the subject of increasing debate among bioethicists, policymakers, and public health ...
Laura Florence Harris   +7 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Lifting the objection permanently

open access: yes, 2021
İcra Hukuku’nda geniş bir uygulama alanı bulan genel haciz yoluyla takipte ödeme emrine itiraz üzerine takip durur. Bu hâlde takibe devam etmek isteyen alacaklının elinde itirazın hükümden düşürülmesini sağlayan bazı hukukî çareler mevcuttur ...
Tanır, Zeliha Büşra
core  

Objection-criminal ruling in Jordanian Courts (Law of 2017)

open access: yesInternational Review of Law, 2021
The objection as regards the judgment in absentia is one of the common ways to challenge criminal rulings, as it raises several issues when lawsuits objection is considered ; whether these issues relate to the notifications or to the rulings that are ...
حسن عوض سالم الطراونه
doaj   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Resistance to Objection in Nonfiction Discourse: Promotive and News Text

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics
The topicality of the study of nonfiction journalistic discourse concerning the communicative action of objection is connected with the existing changes which happened in the perception of science by the public and the journalistic interpretation of this
Natalia A. Prokofeva   +1 more
doaj   +1 more source

SPEECH ACTS OF OBJECTION IN THE PLAY LOOK BACK IN ANGER BY JOHN OSBORNE [PDF]

open access: yesHum, 2011
This paper studies speech acts of objection within local pragmatic acts extracted from the play Look Back in Anger by John Osborne. In this analysis the theoretical postulates in J.L. Austin, J. Searle and speech act theory, Politeness Principle by P.
Daniela Matić
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Conscientious Objection and Harm Reduction in Europe

open access: yes, 2016
Conscientious objection to the provision of health care raises important philosophical and practical questions. Is it justifiable for a health care professional to act against a legal obligation on the grounds that such an action would bring her in ...
FLETCHER, R
core  

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