Results 201 to 210 of about 1,517,059 (245)

Motivation, self-evaluation, performance: comparison of objective and subjective health indicators in higher education. [PDF]

Front Sports Act Living
Fügedi B, Molnár A, Beregi E.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Sleep Characteristics and Menstrual Cycle Phase-Based Differences in Sleep in Naturally Menstruating Elite Female Team Sport Athletes. [PDF]

Eur J Sport Sci
McGeever A, Mallon N, Bruinvels G, Pedlar CR, Doherty R, van Someren KA.   +5 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Physiological Responses During Phacoemulsification Cataract Surgery and Perceived Stress Among Ophthalmology Trainees: A Cross-Sectional Study. [PDF]

Clin Ophthalmol
Doostparast A, Kermani B, Semnani F, Ghandhari M, Zarei-Ghanavati S, Eslampoor A.   +5 more
europepmc   +1 more source

Academic performance and college students' subjective well-being. [PDF]

Front Public Health
Zhai Q, Li Q, Wagan SA.
europepmc   +1 more source

Problematic Digital Behaviors, Procrastination, and Psychological Well-Being: An Integrative Explanatory Model of Happiness in Young Adults. [PDF]

Alpha Psychiatry
Carrasco-Reig M, López-Palanca I, Martí-Vilar M, González-Sala F, Esparza-Reig J.   +4 more
europepmc   +1 more source

Stress perception, academic motivation, and mental well-being: evidence from Chinese undergraduate students. [PDF]

Front Psychol
Hao S, Xu X, Wang X, Chai G, Wei W.
europepmc   +1 more source