Results 61 to 70 of about 23,660,772 (290)
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Dimensions of Well-being and the Millennium Development Goals [PDF]
Well-being and happiness, individually and collectively, is a main indicator of a good life. This paper attempts to implement empirically some of the multidimensional concepts of human well-being by using data from the ‘Pakistan Living Standards ...
Uzma Zia, Rashida Haq
core
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Measuring what matters: the role of well-being methods in development policy and practice [PDF]
In this paper we explore how the measurement of human well-being might contribute to making development policy and practice more effective. While most of the current initiatives are to develop measures of well-being at the level of the nation state (for ...
Coulthard, Sarah +2 more
core
2017 Well Being Trust Annual Report
Tyler Norris, writing in the 2017 Well Being Trust Annual Report: This is a promising moment for our nation, as the importance of mental health and well-being become obvious to growing numbers of Americans and awareness of mental health disorders ...
Well Being Trust
core +1 more source
The distribution of well-being in Ireland [PDF]
Objectives: There is a substantial knowledge gap about the distribution of mental heath in community populations. The European Social Survey is particularly useful as it contains information on over 40,000 individuals, including 2,286 Irish adults.
Doyle, Orla +3 more
core +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Longitudinal evidence for a midlife nadir in human well-being : results from four data sets [PDF]
There is a large amount of cross-sectional evidence for a midlife low in the life cycle of human happiness and well-being (a ‘U shape’). Yet no genuinely longitudinal inquiry has uncovered evidence for a U-shaped pattern.
Terence C. Cheng +6 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

