Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
MDFE-Net: a multiscale dilated feature enhancement network for small object detection. [PDF]
Liu T, Lin S, Zhang J, Li B, Zhu J.
europepmc +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Multi-institutional MRI-based radiomic pilot study to measure the variations between scanner vendors and imaging sessions. [PDF]
Duong S +14 more
europepmc +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The visual perception of relative mass from object collisions. [PDF]
Todd JT, Norman JF.
europepmc +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Small target detection of floating objects in river channels based on improved YOLOv7. [PDF]
Yang W +13 more
europepmc +1 more source
Camouflaged object detection via context and texture-aware hierarchical interaction. [PDF]
Wang Z, Deng Y, Shen C, Zhang M, Lu X.
europepmc +1 more source
Robust 3D Multi-Object Tracking via 4D mmWave Radar-Camera Fusion and Disparity-Domain Depth Recovery. [PDF]
Xie Y +6 more
europepmc +1 more source

